Table 2.  Primary target genes down regulated by p53
Accession			Ratio of gene expression at specific time points
No.
				-CHX				+CHX
	hr.	2	6	12	24	2	4	6	9	12
	Apoptosis
U45878	Inhibitor of Apoptosis protein 1(MIHB)	-4	-8	-3.9	-3.5	-1.9	-1.8	-2.8	-3.1	-2.6
U37546	Inhibitor of Apoptosis protein 2(MIHC)	-4.2	-10.7	-14.9	-15.8	-2.8	-2.8	-3	-3.7	-3.2
	Angiogenesis
L22548	Collagen type XVIII alpha 1	-8.4	-8.4	-8.4	-7.6	-2.9	-2.9	-2.9	-2.9	-2.9
	Cell Cycle
L78833	BRCA-1	-2.9	-3.1	-3.1	-3.1	-4.1	-4.5	-4.5	-2.3	-4.5
M74093	Cyclin E	-0.8	-2.9	-4	-3.2	-1.4	-2.6	-6.9	-4.5	-3.7
U77949	Cdc6-related protein	-2.2	-3.3	-5.9	-6.4	-4.9	-4.4	-9.1	-1.6	-2.1
M72885	GOS2	-33.4	-137	-172	-143	-9.3	-15.1	-11.5	-21	-107
	DNA Repair/Replication
M96684	Purine rich element binding protein A	-4.2	-9.3	-3	-2.5	-1.5	-3.5	-5.3	-5.3	-2.4
	Receptors/ECM
U31201	Laminin gamma 2 chain	-8.5	-8.5	-8.5	-8.5	-2	-2.7	-7.1	-2.4	-3.9
U90716	Caxsackie virus and adenovirus receptor	-5.4	-3.2	-4.3	-2.5	-2.8	-3	-4.2	-2.3	-1.1
U60975	Receptor gp250 precursor	-2.9	-5.6	-1.9	-3.1	-1.5	-1.3	-6.3	-3.4	-2.8
J04970	Carboxypeptidase M	-6.2	-6.2	-5.8	-6.2	-6.9	-6.9	-6.9	-6.1	-6.9
U17566	Folate transporter	-0.8	-2.8	-10.3	-10.3	-3	-8.8	-10.3	-2.6	-2.5
	Metabolism
U00238	Glutamine PRPP amidotransferase	-1.6	-3	-3.5	-3.9	-1.6	-2	-7.2	-9.2	-4.5
	Neuronal Growth
D11428	Peripheral myelin protein 22	-0.3	-2.7	-2.7	-2.7	-3.5	-2.9	-10.9	-9.2	-10.7
S78296	Neurofilament-66	-5.8	-6.9	-5.1	-6.1	-2.6	-2.6	-6.1	-2.8	-2.2
U79255	Amyloid B-precursor binding protein	-0.6	-8.3	-8.3	-8.3	-5	-5	-2.5	-5	-5
U73960	ADP-ribosylation factor-like protein 4	-4.7	-3.4	-6.4	-9.8	-1.4	-2.2	-5.9	-5.9	-4.2
	Transcription
U80017	Basic transcription factor 2 p44	-2.3	-2.6	-2.7	-3.1	-1.5	-2.2	-8	-4	-3.3
X16706	Fra-2	-1.9	-5.4	-5.4	-5.4	-3.9	-2.8	-2	-1.9	-3.1
	Other
HG2855	HSP 70	-1.9	-2.6	-2.9	-3.4	-1	-1.3	-3.1	-6.9	-20.2
L19183	MAC30	-3.2	-2.9	-3.3	-4	-2	-2.7	-3.8	-2.7	-3.4
AB000467	RES4-25	-2.4	-5	-5	-5	-2.1	-1.1	-6.3	-2.5	-6.3
U79273	Clone 23933	-4.9	-16.3	-2.5	-3.6	-4.2	-4.2	-4.2	-4.2	-2.7