Full gene sets (before application of Signature Algorithm) Gene set: RP (S. cerevisiae) 1) EFB1; TEF5; YAL003W Translation elongation factor EF-1beta, GDP/GTP exchange factor for Tef1p/Tef2p 2) RPL19B; YBL0424; YBL027W Ribosomal protein L19 (yeast L23; YL14; rp15L; rp33; rat L19), nearly identical to Rpl19Ap 3) URA7; YBL0410; YBL039C CTP synthase final step in pyrimidine biosynthesis pathway 4) RPS8A; (RPS14A); (RP19); YBL06.05; YBL0613; YBL072C Ribosomal protein S8 (yeast S14; YS9; rp19; mammalian S8), identical to Rps8Bp 5) RPL23A; YBL0713; YBL087C Ribosomal protein L23 (yeast L17a; YL32; E. coli L14; rat L23), nearly identical to Rpl23Bp 6) RPL32; YBL0838; YBL092W Ribosomal protein L32 7) RPL4A; RPL2A; YBR0315; YBR031W Ribosomal protein L4 (yeast L2; YL2; rp2; Xenopus L1; Drosophila L1; rat L4), nearly identical to Rpl4Bp 8) RPS11B; YBR0501; YBR048W Ribosomal protein S11 (yeast S18, YS12, rp41, E. coli S17, human and rat S11), identical to Rps11Bp 9) GRS1; YBR0917; YBR121C Glycyl-tRNA synthetase, also involved in 3'-end formation of mRNA 10) RPS6B; (RPS10A); RPS101; YBR1244; YBR181C Ribosomal protein S6 (yeast S10; YS4; rp9; human, mouse, and rat S6), identical to Rps6Ap 11) RPS9B; SUP46; RPS13A; YBR1317; YBR189W Ribosomal protein S9 (yeast S13, YS11, YP28, rp21, E. coli S4, rat S9), nearly identical to Rps9Ap 12) RPL21A; URP1A; URP1; YBR1401; YBR191W Ribosomal protein L21 (rat L21), nearly identical to Rpl21Bp 13) RPS14A; CRY1; (RP59); YCR59; YCR031C Ribosomal protein S14A (rp59, E. coli S11, rat and human S14) involved in cryptopleurine resistance,nearly identical to Rps14Bp 14) FEN1; GNS1; VBM2; ELO2; SYR3; YCR521; YCR34; YCR034W Protein involved in the elongation of fatty acids up to 24 carbons 15) LHP1; YLA1; lhp1; LAH1; D2585; YDL051W Protein homolog to human La autoantigen which binds to and stabilizes pre-tRNA for 3'endonucleolytic cleavage, has an RNA recognition (RRM) domain 16) RPS29B; D2542; YDL061C Ribosomal protein S29 (yeast S36; YS29; rat S29), similar to Rps29Ap 17) RPL31A; D2478; YDL075W Ribosomal protein L31 (yeast L34; YL36; YL28; rat L31), nearly identical to Rpl31Bp 18) RPP1A; RPLA1; (RPA1); YP1ALPHA; L12eIIA; D2450; YDL081C Acidic ribosomal protein P1A (A1 YP1alpha; E. coli L12eIIA; human and ratP1) 19) RPL13A; D2445; YDL082W Ribosomal protein L13 (rat L13), nearly identical to Rpl13Bp 20) RPS16B; D2442; YDL083C Ribosomal protein S16 (rp61R rat S16), identical to Rps16Ap 21) RPL35B; SOS2; D2170; YDL136W Ribosomal protein L35 (rat L35), identical to Rpl35Ap 22) RPL35A; SOS1; D1249; YDL191W Ribosomal protein L35 (rat L35), identical to Rpl35Bp 23) RPL4B; (RPL2B); PZB362; YD8119.17; D3221; YDR012W Ribosomal protein L4 (yeast L2; YL2; rp2; Xenopus L1; Drosophila L1; rat L4), nearlyidentical to Rpl4Ap 24) SES1; SERS PZA462; D9813.01; D3270; YDR023W Seryl-tRNA synthetase, cytoplasmic, member of class II family of aminoacyl-tRNAsynthetases 25) RPS11A; PZA156; D9813.03; D3278; YDR025W Ribosomal protein S11 (yeast S18; YS12; rp41; E. coli S17; human and rat S11), identical toRps11Bp 26) RPS13; YS15; YD9609.18; D4252; YDR064W Ribosomal protein S13 (yeast S27; YS15; rat S13) 27) ASP1; D9798.6; YDR321W Asparaginase, (L-asparagine aminohydrolase I), intracellular isozyme that converts asparagine to aspartate andammonia 28) RPP2B; RPLA4; RPL45; L12eIA; L36; YPA1; D9481.1; D9509.2; YDR382W Acidic ribosomal protein P2B (L45 YPA1; YL44C; YP2 beta E. coliL12eIA; human and rat P2) 29) YDR417C Protein of unknown function 30) RPL12B; D9461.7; YDR418W Ribosomal protein L12 (yeast L15; YL23; E. coli L11; rat L12a), identical to Rpl12Ap 31) TIF35; D9461.16; YDR429C Translation initiation factor eIF3, p33 subunit, contains an RRM (RNA recognition motif) domain 32) RPS17B; RP51B; D9461.32; YDR447C Ribosomal protein S17 (rp51 rat S17), nearly identical to Rpl17Ap 33) RPS18A; YDR450W; RPS13C; D9461.35 Ribosomal protein S18 (E. coli S13; rat S18), identical to Rps18Bp 34) GUK1; NES25; D9461.39; YDR454C Guanylate kinase, carries out conversion of ATP + GMP to ADP + GDP 35) RPL27B; D8035.14; YDR471W Ribosomal protein L27 (yeast L27; mammalian L27), identical to Rpl27Ap 36) RPL37B; D9719.6; YDR500C Ribosomal protein L37 (yeast L46) (rat L37), nearly identical to Rpl37Bp 37) SNU13; YEL026W Component of the U4/U6.U5 snRNP, has similarity to nucleolar snoRNP protein Nhp2p 38) RPL12A; YEL054C Ribosomal protein L12 (yeast L15; YL23; E. coli L11; rat L12b), identical to Rpl12Bp 39) GCD11; SUI4; YER025W Translation initiation factor eIF2 gamma subunit 40) RPS24A; YER074W Ribosomal protein S24 (rat S24), identical to Rps24Bp 41) RPS8B; (RPS14B); (RP19); YER102W Ribosomal protein S8 (yeast S14; YS9; rp19; mammalian S8), identical to Rps8Ap 42) RPL23B; YER117W Ribosomal protein L23 (yeast L17a; YL32; E. coli L14; rat L23), nearly identical to Rpl23Ap 43) RPS26B; YER131W Ribosomal protein S26 (rat S26), nearly identical to Rps26Ap 44) RPL30; (RPL32); G3652; YGL030W Large-subunit ribosomal protein L30 (yeast L32; YL38; rp73; mouse and rat L30) 45) RPL24A; G3648; YGL031C Ribosomal protein L24A (yeast L30; rp29; YL21; rat L24), nearly identical to Rpl24Bp 46) RPL7A; YL8A; G3216; YGL076C Ribosomal protein L7 (yeast L6; YL8A; rp11; E. coli L30; rat L7), nearly identical to Rpl7Bp 47) DBP3; G3210; YGL078C ATP-dependent RNA helicase CA3; member of the DEAD/DEAH box family 48) RPL28; CYH2; G3101; YGL103W Ribosomal protein L28 (yeast L29; YL24; rp44; mouse and rat L27a) 49) RPS2; (RPS4); SUP44; G2893; YGL123W Ribosomal protein S2 (yeast S4; YS5; YP9; rp12; E. coli S5; rat S2) 50) RPL1B; SSM1B; SSM2; G2834; YGL135W Large subunit ribosomal protein L1 (rat L10A; eubacterial L1; archeal L1), identical to Rpl1Ap 51) RPL9A; RP25; YL11; G2505; YGL147C Ribosomal protein L9 (YL11 rp25; rp24; E. coli L6; rat L9), nearly identical to Rpl9Bp 52) RPS25A; RPS31A; G4046; YGR027C Ribosomal protein S25A (yeast S31; YS23; rp45; rat S25), identical to Rps25Bp 53) RPL26B; G4079; YGR034W Ribosomal protein L26 (yeast L33; YL33; rat L26), nearly identical to Rpl26Ap 54) RPL11B; G4620; YGR085C Ribosomal protein L11 (yeast L16; YL22; rp39B; E. coli L5; rat L11), nearly identical to Rpl11Ap 55) RPS23A; (RPS28A); G6178; YGR118W Ribosomal protein S23 (yeast S28; rp37; YS14; E. coli S12; rat S23), identical to Rps23Bp 56) RPL24B; G6635; YGR148C Ribosomal protein L24B (yeast L30; rp29; YL21; rat L24), nearly identical to Rpl24Ap 57) RPS0A; YST1; (NAB1); NAB1A; G7816; YGR214W Ribosomal protein S0 (E. coli S2; rat Sa), nearly identical to Rps0Bp 58) MES1; G9340; YGR264C Methionyl-tRNA synthetase, cytoplasmic, member of class I aminoacyl tRNA synthetase family 59) RPL14B; YHL001W Ribosomal protein L14 (mammalian L14), nearly identical to Rpl14Ap 60) RPS20; URP2; YHL015W Ribosomal protein S20 (E. coli S10; Xenopus S22; rat and human S20) 61) RPL8A; MAK7; YHL033C Ribosomal protein L8 (yeast L4; rp6; YL5; human, mouse, and rat L7a), involved in maintenance of M1 dsRNA virus;nearly identical to Rpl8Bp 62) RPL27A; YHR010W Ribosomal protein L27 (yeast L27; mammalian L27), identical to Rpl27Bp 63) RPS27B; SLO81; YHR021C Ribosomal protein S27 (yeast S27; rp61; YS20; mammalian S27), nearly identical to Rps27Ap 64) PDR13; H8025.17; YHR064C Pleiotropic drug resistance protein, member of the Hsp70 family of heat shock proteins 65) GAR1; YHR089C Protein involved in 35S rRNA processing and pseudouridinylation associated with the H/ACA class small nucleolar RNAs 66) RPL42B; MAK18; SCL41B; YHR141C Ribosomal protein L42 (yeast L41; YL27; YP44; human and rat L36A), involved in replication of M1 and M2double-stranded RNA (dsRNA) viruses, identical to Rpl42Ap 67) NMD3; SRC5; YHR170W Protein involved in the nuclear export of 60S ribosomal subunits 68) EGD2; H9998.17; YHR193C Alpha subunit of the nascent polypeptide-associated complex 69) RPS4B; (RPS4); (RPS7A); YHR203C Ribosomal protein S4 (yeast S7; YS6; rp5; rat and human S4), identical to Rps4Ap 70) RPL2B; RPL5A; YL6b; YI3299.13; YIL018W Ribosomal protein L2 (yeast L5; YL6; rp8; E. coli L2; tobacco L2; rat L8) 71) RPL34B; YIL052C Ribosomal protein L34 (rat L34), nearly identical to Rpl34Ap 72) RPL16A; YIL133C Ribosomal protein L16 (rp22), nearly identical to Rpl16Bp 73) RPL40A; UBI1; CEP52A; CST2; YIL148W Fusion protein whose N-terminal half is ubiquitin and whose C-terminal half is ribosomal protein L40(rat L40), identical to Rpl40Bp 74) RPS21B; (RPS26B); J0664; YJL136C Ribosomal protein S21 (yeast S26; YS25; rat S21), identical to Rps21Ap 75) TIF2; J0660; YJL138C Translation initiation factor 4A (eIF4A) of the DEAD box family, identical to Tif1p 76) RPL17B; J0493; YJL177W Ribosomal protein L17 (yeast L20; YL17; E. coli L22; rat and human L17), nearly identical to Rpl17Ap 77) RPS22A; (RPS24); J0355; YJL190C Ribosomal protein S22 (yeast S24; rp50; YS22; rat S15A), nearly identical to Rps22Bp 78) RPS14B; CRY2; (RP59); J0354; J0353; YJL191W Ribosomal protein S14B (rp59 E. coli S11; rat and human S14), nearly identical to Rps14Ap 79) YJR070C; J1814 Protein of unknown function 80) RPS5; J2045; YJR123W Ribosomal protein Rps5p (rp14 YS8; S2; mammalian S5) of the small subunit 81) RPS4A; (RPS4); (RPS7B); J2186; YJR145C Ribosomal protein S4 (yeast S7; YS6; rp5; rat and human S4), identical to Rps4Bp 82) RPL14A; YKL153; YKL006W Ribosomal protein L14 (mammalian L14), nearly identical to Rpl14Bp 83) MRT4; YKL160; YKL009W Protein involved in mRNA turnover 84) YKL056C; YKL312 Protein possibly involved in cytoplasmic ribosome function, has similarity to translationally controlled tumor protein (TCTP) ofanimal cells and higher plants 85) RPS27A; YKL156W Ribosomal protein S27 (yeast S27; rp61; YS20; mammalian S27), nearly identical to Rps27Bp 86) RPL17A; YKL180W Ribosomal protein L17 (yeast L20; YL17; E. coli L22; rat and human L17), nearly identical to Rpl17Bp 87) PRS1; PRPS1; (PPS1); YKL181W Phosphoribosylpyrophosphate synthetase, synthesizes phosphoribosylpyrophosphate (PRPP) from ribose-5'phosphate and ATP, involved in pseudohyphal growth 88) RPS21A; (RPS26A); YKR057W Ribosomal protein S21 (yeast S26; YS25; rat S21), identical to Rps21Bp 89) TIF1; YKR059W Translation initiation factor 4A (eIF4A) of the DEAD box family, identical to Tif2p 90) RPL40B; UBI2; CEP52B; CST1; YKR414; YKR094C Fusion protein comprised of ribosomal protein L40 (C-terminal half) and ubiquitin(N-terminal half), (rat L40), identical to Rpl40Ap 91) YLL044W; L0725 Protein of unknown function 92) RPL8B; KRB1; L0717; YLL045C Ribosomal protein L8 (yeast L4; rp6; YL5; human, rat, and mouse L7a), involved in maintenance of M1 dsRNAvirus nearly identical to Rpl8Ap 93) RPL15A; L1755; YLR029C Ribosomal protein L15 (yeast L13; YL10; rp15R; rat L15), nearly identical to Rpl15Bp 94) RPS0B; YST2; NAB1B; L2118; YLR048W Ribosomal protein S0 (E. coli S2; rat Sb), nearly identical to Rps0Ap 95) RPL22A; YL31; L2168; YLR061W Ribosomal protein L22, similar to Rpl22Bp 96) BUD28; L2171; YLR062C Protein that may be involved in bud site selection in diploid cells 97) RPL10; GRC5; QSR1; L2341; YLR075W Ribosomal protein L10 (yeast L9) 98) STM1; MPT4; (STO1); G4P2; L9634.1; L3321; YLR150W Protein with specific affinity for guanine-rich quadruplex nucleic acids multicopysuppressor of pop2 and tom1 99) RPS31; UBI3; L9470.14; YLR167W Fusion protein comprised of ribosomal protein S31 at the C-terminal half fused to ubiquitin at the N-terminalhalf (yeast S37; YS24; rat S27a) 100) CBF5; LUC8; (ART1); L9470.11; YLR175W Putative ribosomal RNA pseudouridine synthase, associated with H/ACA class small nucleolarRNAs 101) RPL37A; L9470.6; YLR185W Ribosomal protein L37 (yeast L46; rat L37), nearly identical to Rpl37Bp 102) SIK1; NOP56; L8167.9; YLR197W Nucleolar protein component of box C/D snoRNPs, which are necessary for 2'-O-methylation of ribosomalRNAs 103) YEF3; YEF3A; (TEF3); (EFC1); L9672.5; YLR249W Translation elongation factor EF-3A, member of the non-transporter group of the ATP-bindingcassette (ABC) superfamily 104) RPS28B; L8479.5; YLR264W Ribosomal protein S28 (yeast S33; YS27; mammalian S28), nearly identical to Rps28Ap 105) RPL38; L8543.2; YLR325C Ribosomal protein L38 106) RPS25B; RPS31B; L8300.10; YLR333C Ribosomal protein S25B (yeast S31; YS23; rp45; rat S25), identical to Rps25Ap 107) RPP0; RPLA0; RPA0; L10e; YSCA0; L8300.8; YLR340W Acidic ribosomal protein A0 108) RPL26A; L8300.4; YLR344W Ribosomal protein L26 (yeast L33; YL33; rat L26), nearly identical to Rpl26Bp 109) RPS22B; (RPS24); L8039.6; YLR367W RIbosomal protein S22 (yeast S24; rp50; YS22; rat S15A), nearly identical to Rps22Ap 110) SUR4; (APA1); VBM1; ELO3; SRE1; L8039.2; YLR372W Protein required for the conversion of 24-carbon fatty acids to 26-carbon fatty acids 111) RPS29A; L8084.11; YLR388W Ribosomal protein S29 (yeast S36; YS29; rat S29), similar to Rps29Bp 112) RPS1A; RP10A; (PLC1); L9753.9; YLR441C Ribosomal protein S1 (rp10 rat S3A), nearly identical to Rps1Bp 113) RPL6B; L9324.4; YLR448W Ribosomal protein L6 (yeast L17B; YL16B; human L6), nearly identical to Rpl6Ap 114) FPR4; L9324.3; YLR449W Nucleolar peptidylprolyl cis-trans isomerase (PPIase) 115) APT1; YML022W Adenine phosphoribosyltransferase (APRT), may be a heterodimer with Apt2p 116) RPS17A; RP51A; YML024W Ribosomal protein S17 (rp51 rat S17), nearly identical to Rps17Bp 117) RPS18B; YML026C Ribosomal protein S18 (E. coli S13; rat S18), identical to Rps18Ap 118) IMD4; YM9958.06; YML056C Protein with similarity to inosine-5'-monophosphate dehydrogenase 119) RPS1B; RP10B; RP3B; PLC2; KRP-Y1; YML063W Ribosomal protein S1 (rp10 rat S3A), nearly identical to Rps1Ap 120) RPL6A; YML073C Ribosomal protein L6 (yeast L17A; YL16A; human L6), nearly identical to Rpl6Bp 121) URA5; PYR5; YM8339.13; YML106W Orotate phosphoribosyltransferase 1, catalyzes the fifth step in the pyrimidine biosynthesis pathway 122) ASC1; BEL1; CPC2; YM9718.15; YMR116C Ribosomal protein of the 40S ribosomal subunit that influences translational efficiency and cell size,contains two WD (WD-40) repeats 123) RSA2; YM9553.07; YMR131C Protein involved in ribosome assembly, member of WD (WD-40) repeat family 124) RPL13B; YM9375.11; YMR142C Ribosomal protein L13 (rat L13), nearly identical to Rpl13Ap 125) RPL36A; YM9646.06; YMR194W Ribosomal protein L36 (yeast L39; YL39; rat L36), nearly identical to Rpl36Bp 126) GUA1; YM8261.11; YMR217W GMP synthetase, catalyzes the amination of xanthine monophosphate to guanine monophosphate in the guaninebranch of the purine biosynthesis pathway 127) RPS10B; YM9959.12; YMR230W Ribosomal protein S10 (rat S10), nearly identical to Rps10Ap 128) RPL20A; YM9408.04; YMR242C Ribosomal protein L20, nearly identical to Rpl20Bp 129) TIF11; YM8156.02; YMR260C Translation initiation factor eIF1A 130) RPL9B; N2406; YNL1611; YNL2406; YNL067W Ribosomal protein L9 (YL11 rp25; rp24; E. coli L6; rat L9), nearly identical to Rpl9Ap 131) RPL16B; N2377; YNL069C Ribosomal protein L16 (rp23), nearly identical to Rpl16Ap 132) RPS7B; N2212; YNL096C Ribosomal protein S7 (rp30 human S7; Xenopus S8), nearly identical to Rps7Ap 133) RPL42A; SCL41A; N1722; YNL162W Ribosomal protein L42 (yeast L41; YL27; YP44; human and rat L36A), identical to Rpl42Bp 134) RPS3; RP13; SUF14; N1653; YNL178W Ribosomal protein S3 (rp13 YS3; mammalian S3), has a possible KH domain 135) SSB2; N1333; YNL209W Heat shock protein of HSP70 family, cytoplasmic 136) RPA49; N0880; YNL248C RNA polymerase I third largest subunit 137) GIS2; N0852; YNL255C Protein possibly involved in cytoplasmic ribosome function has similarity to nucleic acid binding proteins 138) RPL18B; RP28B; N0425; YNL0425; YNL301C Ribosomal protein L18 (rp28 rat L18), identical to Rpl18Ap 139) RPS19B; RP55B; (RPS16B); N0422; YNL0422; YNL302C Ribosomal protein S19 (rp55 YS16B; rat S19), nearly identical to Rps19Ap 140) RPP2A; RPLA2; RPL44; (RPA2); L12eIB; L35; O2060; YOL039W Acidic ribosomal protein P2A (L44 A2; YP2alpha; E. coli L12eIB; humanP2alpha), plays a role in the elongation step 141) RPS15; RPS21; O2057; YOL040C Ribosomal protein S15 (yeast S21; rp52; E. coli S19; rat S15; RIG protein) 142) BRX1; O1115; YOL077C Protein required for biogenesis of the 60S ribosomal subunit, localized to the nucleolus 143) WRS1; HRE432; O0792; YOL097C Tryptophanyl-tRNA synthetase 144) RPL18A; RP28A; O0565; YOL120C Ribosomal protein L18 (rp28 rat L18), identical to Rpl18Bp 145) RPS19A; RP55A; (RPS16A); O0559; YOL121C Ribosomal protein S19 (rp55 YS16A; rat S19), nearly identical to Rps19Bp 146) RPL25; O0534; YOL127W Ribosomal protein L25 (YL25 rp61L; E. coli L23; rat L23a) 147) CDC33; TIF45; AOE213; O0480; YOL139C Translation initiation factor eIF4E, mRNA cap-binding protein found in association with Caf20p 148) RPL3; TCM1; MAK8; O2812; YOR29-14; YOR063W Ribosomal protein L3 (YL1 rp1; rat L3) , responsible for trichodermin resistance andinvolved in maintenance of dsRNA viruses 149) RPS7A; RP30; YOR3177; O3177; YOR096W Ribosomal protein S7 (rp30 human S7; Xenopus S8), nearly identical to Rps7Bp 150) RPS28A; O3598; YOR167C Ribosomal protein S28 (yeast S33; YS27; mammalian S28), nearly identical to Rps28Bp 151) RPB8; YOR50-14; O5014; O5070; YOR224C Shared subunit of RNA polymerases I, II, and III (ABC14.5) 152) RPL33B; O5224; YOR234C Ribosomal protein L33 (yeast L37; YL37; rp47; rat L35A), nearly identical to Rpl33Ap 153) CAF20; CAP20; CAF2; O5453W; YOR276W mRNA cap-binding protein (eIF4F) 20K subunit 154) RPS10A; O5611; YOR293W Ribosomal protein S10 (rat S10), nearly identical to Rps10Bp 155) YOR309C; O6105 Protein of unknown function 156) NOP5; NOP58; LUC9; O6108; YOR310C Nucleolar protein component of box C/D snoRNPs involved in 2'-O-methylation of ribosomal RNAs 157) RPL20B; O6116; YOR312C Ribosomal protein L20, nearly identical to Rpl20Ap 158) RPS12; RS12; O6673; YOR369C Ribosomal protein S12 (rat S12) 159) EGD1; CST25; P7102.13; YPL037C Beta subunit of the nascent polypeptide-associated complex 160) RPL21B; URP1B; LPF6; YPL079W Ribosomal protein L21 (rat L21), nearly identical to Rpl21Ap 161) RPS9A; RPS13B; (YS11A); YPL081W Ribosomal protein S9 (yeast S13; YS11; YP28; rp21; E. coli S4; rat S9), nearly identical to Rps9Bp 162) RPS6A; (RPS10B); RPS102; LPG18; YPL090C Ribosomal protein S6 (yeast S10; YS4; rp9; human, mouse, and rat S6), identical to Rps6Bp 163) RPL5; RPL1; YL3; LPI14; YPL131W Ribosomal protein L5 (yeast L1; YL3; rat L5), the sole 5S rRNA-associated ribosomal protein 164) RPL33A; LPI4; P2625; YPL143W Ribosomal protein L33 (yeast L37; YL37; rp47; rat L35A), nearly identical to Rpl33Bp 165) NIP7; P1810; YPL211W Nucleolar protein required for efficient 60S ribosome subunit biogenesis 166) RPL1A; SSM1A; SSM1; P1740; YPL220W Large subunit ribosomal protein L1 (rat L10A; eubacterial L1; archeal L1), identical to Rpl1Bp 167) SUI3; P1054; YPL237W Translation initiation factor eIF2beta subunit 168) RPL11A; P8283.14; YPR102C Ribosomal protein L11 (yeast L16; YL22; rp39A; E. coli L5; rat L11), nearly identical to Rpl11Bp 169) RPC40; RPC5; P8283.18; YPR110C Shared subunit of RNA polymerases I and III 170) RPS23B; (RPS28B); P9659.9; YPR132W Ribosomal protein S23 (yeast S28; rp37; YS14; E. coli S12; rat S23), identical to Rps23Ap 171) TIF3; (STM1); RBL3; IF4B; P9325.6; YPR163C Translation initiation factor eIF4B, contains one RRM (RNA recognition motif) RNA-bindingdomain 172) RPO26; RPB6; P9677.8; YPR187W Shared subunit of RNA polymerases I, II, and III (ABC23) 173) RPL19A; YBR084C-A Ribosomal protein L19 (yeast L23; YL14; rp15L; rp33; rat L19), nearly identical to Rpl19Bp 174) RPL34A; YER056C-A Ribosomal protein L34 (rat L34), nearly identical to Rpl34Bp 175) RPL2A; YL6; YFR031C-A Ribosomal protein L2 (Yeast L5; YL6; rp8; E. coli L2; tobacco L2; rat L8) ----------------------------------------------- Gene set: RP (C. albicans) 1) "3838|EFB1|YAL003w,3E-33|C:ribosome (ISS)|F:translation elongation factor (ISS)|P:translational elongation (ISS)|translation elongation factor eEF1beta | GDP/GTP exchange factor for Tef1p/Tef2p|4F2" 2) "5904|RPL19A|YBR084ca,6E-37|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein L19A (L23A) (rpl5L) (YL14)|3P \ 3O" 3) "3941|URA7|YBL039c,e-157|C:cytosol (ISS)|F:CTP synthase (ISS) | F:CTP synthase (ISS)|P:phospholipid biosynthesis (ISS) | P:pyrimidine base biosynthesis (ISS)|CTP synthase|5I" 4) 3415.1|RPL32|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|60S large subunit ribosomal protein L32.e|6O 5) "437|GRS1|YBR121c,e-179|C:cytoplasm (ISS) | C:mitochondrion (ISS)|F:glycine- tRNA ligase (ISS) | F:glycine-tRNA ligase (ISS)|P:glycyl- tRNA aminoacylation (ISS) | P:glycyl-tRNA aminoacylation (ISS) | P:transcription termination (ISS)|glycyl-tRNA synthase | glycine-tRNA ligase|1" 6) "838.1|RPS9B|YPL081w,4E-30|C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS) | P:regulation of translational fidelity (ISS)|ribosomal protein S9B|2U" 7) "840|RPL21A|YBR191w,1E-38|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein L21|2U" 8) "6343|FEN1|YCR034w,1E-89|C:endoplasmic reticulum membrane (ISS)|F:molecular_function unknown (ND)|P:fatty acid elongation (ISS) | P:non-selective vesicle transport (ISS) | P:sphingolipid biosynthesis (ISS)|involved in synthesis of 1,3-beta-glucan, a component of the cell wall, and elongation of fatty acids up to 24 carbons | 1,3-beta-glucan synthase subunit | fatty acid elongase required for sphingolipid formation|1" 9) "2795|LHP1|YDL051w,0.0000000000000004|C:nucleus (ISS)|F:RNA binding (ISS)|P:tRNA processing (ISS)|RNA binding protein similar to human La antigen|1" 10) "2992|RPA1|YDL081c,0.00000000000001|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:translational elongation (ISS) | P:translational elongation (ISS)|60S ribosomal protein|1SZ" 11) "2994|RPL13|YDL082w,2E-45|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein|1SZ" 12) 2994.1|RPS16|C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein|1SZ 13) 5964.2|RPL35|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein L35A|3P \ 3O 14) "7217|RPL4|YDR012w,1E-90|C:cytoplasm (ISS) | C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein L4B|1S" 15) "269|SES1|YDR023w,e-143|C:cytoplasm (ISS)|F:serine-tRNA ligase (ISS)|P:amino acid activation (ISS)|seryl-tRNA synthetase|3O" 16) 4193.1|RPS13|C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein S13 (S27a) (YS15)|6O 17) "7593|ASP1|YDR321w,6E-61|C:cell (ISS)|F:asparaginase (ISS)|P:aspartate biosynthesis (ISS)|L-asparaginase|RD \ RD2" 18) "5928|RPP2B|YDR382w,0.000000000001|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:translational elongation (ISS) | P:translational elongation (ISS)|acidic ribosomal protein P2B | ribosomal protein P2B (YP2beta) (L45)|3P \ 3O" 19) "7236|TIF35|YDR429c,7E-33|C:eukaryotic translation initiation factor 3 complex (ISS) | C:eukaryotic translation initiation factor 3 complex (ISS)|F:translation initiation factor (ISS)|P:translational initiation (ISS)|translation initiation factor eIF3, p33 subunit|1S" 20) "2329.1|RPS17B|YKL012w,8E-35|C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS) | P:ribosomal small subunit assembly and maintenance (ISS)|ribosomal protein S17.e.B|1" 21) "1115|GUK1|YDR454c,1E-50|C:cellular_component unknown (ND)|F:guanylate kinase (IEA)|P:GMP metabolism (ISS)|guanylate kinase|5" 22) 667.1|RPL37B|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein L37B|1E 23) "5885|SNU13|YEL026w,8E-31|C:nucleolus (ISS) | C:small nuclear ribonucleoprotein complex (ISS) | C:small nucleolar ribonucleoprotein complex (ISS)|F:pre-mRNA splicing factor (ISS) | F:snoRNA binding (ISS)|P:mRNA splicing (ISS) | P:processing of 20S pre-rRNA (ISS)|part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA)|3P \ 3O" 24) "1635|RPL12|YEL054c,6E-48|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS) | P:ribosomal large subunit assembly and maintenance (ISS)|large subunit ribosomal protein L12.e|3O" 25) "4223|EIF2|YER025w,e-160|C:ribosome (ISS)|F:translation initiation factor (ISS)|P:translational initiation (ISS)|translation initiation factor|5M" 26) "6873|RPS8|YER102w,2E-46|C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein S8E|2" 27) "3504|RPL23|YER117w,3E-38|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|ribosomal protein|6O" 28) 3788.1|RPL30|C:cytoplasm (ISS) | C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS) | F:structural constituent of ribosome (ISS)|P:mRNA splicing (ISS) | P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS) | P:rRNA processing (ISS) | P:regulation of translation (ISS)|ribosomal protein L30 (L32) (rp73) (YL38) large subunit|4F2 29) 3789|RPL24A|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:RNA binding (ISS) | F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein L24A (rp29) (YL21) (L30A)|4F2 30) 2478.1|RPL7B|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|60S large subunit ribosomal protein|1 31) "4870|DBP3|YGL078c,e-111|C:nucleolus (ISS)|F:ATP dependent RNA helicase (ISS)|P:35S primary transcript processing (ISS) | P:ribosomal large subunit assembly and maintenance (ISS)|ATP-dependent RNA helicase CA3 of the DEAD/DEAH box family|1J \ 1S" 32) "3334|RPS2|YGL123w,1E-58|C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS) | P:regulation of translational fidelity (ISS)|ribosomal protein|1SZ" 33) "6663|RPS25|YLR333c,0.000000000000000005|C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein S25|5I" 34) "2232|RPL11|YPR102c,5E-54|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS) | P:ribosomal large subunit assembly and maintenance (ISS)|ribosomal protein L11A|2U" 35) "6975|RPS0A|YGR214w,3E-57|C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS) | P:ribosomal small subunit assembly and maintenance (ISS)|ribosomal protein S0A|3" 36) "3955|MES1|YGR264c,0|C:cytoplasm (ISS)|F:methionine-tRNA ligase (ISS) | F:methionine-tRNA ligase (IEA)|P:amino acid activation (ISS)|methionyl tRNA synthetase|5I" 37) 4931.1|RPL14B|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:RNA binding (ISS) | F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein L14B|1L 38) "6375|RPS20|YHL015w,1E-27|C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein S20|RS or RU" 39) 5225.2|RPL27|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein L27|1L 40) 6286.2|RPS27|C:cytoplasm (ISS) | C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein S27|5 41) "3812|SSZ1|YHR064c,3E-89|C:cytoplasm (ISS)|F:chaperone ((ISS)) | F:chaperone (ISS) | F:chaperone (ISS)|P:protein biosynthesis ((ISS)) | P:protein biosynthesis ((ISS)) | P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|regulator protein involved in pleiotropic drug resistance that forms a ribosome-associated complex | DnaJ/HSP70 chaperone|4F2" 42) "1164|GAR1|YHR089c,2E-31|P:35S primary transcript processing (ISS) | P:rRNA modification (ISS)|nucleolar rRNA processing protein|1X" 43) "706|NMD3|YHR170w,e-115|C:cytosol (ISS) | C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:RNA binding (ISS) | F:protein binding (ISS)|P:ribosomal large subunit assembly and maintenance (ISS)|nonsense mRNA degradation; ribosomal assembly|R" 44) "5858|EGD2|YHR193c,9E-24|C:nascent polypeptide-associated complex (ISS)|F:chaperone (ISS)|P:nascent polypeptide association (ISS)|GAL4 enhancer protein|3P \ 3O" 45) 2309.2|RPL2B|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|60S large subunit ribosomal protein L2B|1 46) "6085|RPL16B|YNL069c,4E-56|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:RNA binding (ISS) | F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|60S large subunit ribosomal protein|1S" 47) "4490|RPL17B|YJL177w,8E-52|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein L17B|2" 48) "6265|RPS22|YJL190c,7E-43|C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein|1J" 49) 6265.1|RPS14|C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:RNA binding (ISS) | F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS) | P:ribosomal small subunit assembly and maintenance (ISS)|ribosomal protein|1J 50) "2286|YJR070c,2E-70|phycocyanin alpha-subunit phycocyanobilin lyase|2U" 51) "4336|RPS5|YJR123w,3E-59|C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal small subunit protein|5M" 52) "5341|RPS4|RPS4|YJR145c,1E-79|C:cytoplasm (ISS) | C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein S4|2AX" 53) "5550|MRT4|YKL009w,1E-65|C:cellular_component unknown (ND)|F:molecular_function unknown (ND)|P:ribosomal large subunit biogenesis (ISS) | P:ribosomal large subunit biogenesis (ISS)|required for mRNA decay|6O" 54) "3268|YKL056c,6E-43|translationally controlled tumor protein|2U ?" 55) "969|PRS2|YKL181w,e-102|C:cytoplasm (ISS)|F:ribose-phosphate pyrophosphokinase (ISS)|P:'de novo' IMP biosynthesis (ISS) | P:'de novo' pyrimidine base biosynthesis (ISS) | P:histidine biosynthesis (ISS) | P:purine salvage (ISS) | P:tryptophan biosynthesis (ISS)|ribose-phosphate pyrophosphokinase|5M" 56) 3325.3|RPS21B|C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|40S ribosomal protein S21 (S26) (YS25)|1SZ 57) "3324|TIF1|TIF1|YKR059w,e-110|C:ribosome (ISS)|F:translation initiation factor (ISS)|P:translational initiation (ISS)|translation initiation factor 4A|1SZ" 58) "6002|RPL8B|YLL045c,3E-70|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein L8B (L4B) (rp6) (YL5)|3P \ 3O" 59) "493|RPL15A|YLR029c,8E-66|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:RNA binding (ISS) | F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein L15B|RK \ RS" 60) 2935|RPL10|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS) | P:ribosomal large subunit assembly and maintenance (ISS)|ribosomal protein L10|1SZ 61) 5943.1|STM1|C:cytoplasm (ISS) | C:telomere (ISS)|F:molecular_function unknown (IEA)|P:anti-apoptosis (ISS)|purine motif triplex-binding protein | specific affinity for guanine-rich quadruplex nucleic acids|3P \ 3O 62) "3087|RPS31|YLR167w,8E-36|C:cytoplasm (ISS) | C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS) | P:ribosomal small subunit assembly and maintenance (ISS)|small subunit ribosomal protein|4H" 63) "1833|CBF5|YLR175w,e-133|F:pseudouridylate synthase (ISS)|P:35S primary transcript processing (ISS) | P:rRNA modification (ISS)|nucleolar pseuduridine synthase and putative microtubule binding protein|1" 64) "7569|SIK1|YLR197w,e-128|C:nucleolus (ISS) | C:nucleus (ISS) | C:small nuclear ribonucleoprotein complex (ISS) | C:small nucleolar ribonucleoprotein complex (ISS)|F:snoRNA binding (ISS)|P:35S primary transcript processing (ISS) | P:processing of 20S pre-rRNA (ISS) | P:rRNA modification (ISS)|nucleolar protein involved in pre- rRNA processing|RD \ RD2" 65) "4152|EFT3|EFT3|YNL014w,0|C:cytosolic ribosome (sensu Eukarya) (ISS)|F:ATPase (ISS) | F:translation elongation factor ((ISS)) | F:translation elongation factor (ISS)|P:translational elongation ((ISS))|translation elongation factor|5M" 66) "7015|RPP0|YLR340w,2E-77|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:ribosomal large subunit assembly and maintenance (ISS) | P:translational elongation (ISS) | P:translational elongation (ISS)|ribosomal protein P0 (A0) (L10E)|7C \ 7A" 67) 3690.2|RPL26A|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:RNA binding (ISS) | F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein L26A (L33A) (YL33)|1SZ 68) 3003.1|RPL6|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:RNA binding (ISS) | F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS) | P:ribosomal large subunit assembly and maintenance (ISS)|ribosomal protein|1SZ 69) "1448|APT1|YML022w,6E-46|F:adenine phosphoribosyltransferase (ISS)|P:AMP biosynthesis (ISS)|adenine phosphoribosyltransferase|2U" 70) "7018|RPS18B|YML026c,2E-40|C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein S18B|7C \ 7A" 71) 3002|RPS1|RP10|C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein 10|1SZ 72) "2555|URA5|YML106w,5E-49|C:cytoplasm (ISS)|F:orotate phosphoribosyltransferase (ISS)|P:pyrimidine base biosynthesis (ISS)|orotate phosphoribosyltransferase|RMZ" 73) "6906|ASC1|YMR116c,2E-44|C:cytoplasm (ISS)|F:molecular_function unknown (ND)|P:biological_process unknown (ND)|WD repeat protein that interacts with the translational machinery|7" 74) "6355|RSA2|YMR131c,e-114|C:nucleolus (ISS)|F:molecular_function unknown (IEA)|P:ribosome biogenesis (IEA)|involved in the regulation of ribosome biosynthesis|1" 75) 827.1|RPL39|RPL39|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:RNA binding (ISS) | F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein L39|2U 76) "4813|GUA1|YMR217w,e-175|C:cellular_component unknown (ND)|F:GMP synthase (glutamine hydrolyzing) (IEA)|P:GMP metabolism (ISS)|GMP synthase|1J \ 1S" 77) 2179.2|RPS10|C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein S10A|2U 78) "4632|RPL20B|YOR312c,1E-54|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein L20|4N or 4BB" 79) "5351|TIF11|YMR260c,2E-35|C:ribosome (ISS)|F:translation initiation factor (ISS)|P:translational initiation (ISS)|translation initiation factor eIF1A|2AX" 80) "236|RPL9B|YNL067w,6E-54|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein L9B|3O" 81) 4909.1|RPL42A|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein L42A|1J \ 1S 82) "6312|RPS3|YNL178w,5E-59|C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS) | P:response to DNA damage (ISS)|ribosomal protein S3 (rp13) (YS3)|R" 83) "6367|SSB1|SSB1|YNL209w,0|C:cytoplasm (ISS) | C:polysome (ISS)|F:chaperone (ISS)|P:protein biosynthesis (ISS)|heat shock protein of the HSP70 family|RS or RU" 84) "2017|RPA49|YNL248c,3E-80|C:DNA-directed RNA polymerase I complex (ISS)|F:DNA- directed RNA polymerase I (ISS)|P:transcription from Pol I promoter (ISS)|RNA polymerase I alpha subunit|2U" 85) "3182|GIS2|YNL255c,2E-30|C:cellular_component unknown (ND)|F:transcription factor (ISS)|P:intracellular signaling cascade (ISS)|nucleic acid binding protein|5M" 86) 5996.1|RPS19A|C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein S19A (S16aA) (rp55A) (YS16A)|3P \ 3O 87) "5927|RPS15|YOL040c,8E-36|C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein S15 (S21) (rp52) (RIG protein)|3P \ 3O" 88) 5232|C:nucleolus (ISS)|F:molecular_function unknown (ND)|P:ribosomal large subunit assembly and maintenance (ISS)|conserved hypothetical protein|1L 89) "5226|WRS1|YOL097c,e-130|C:cytoplasm (ISS)|F:tryptophan-tRNA ligase (IEA)|P:tryptophanyl-tRNA aminoacylation (ISS)|tryptophan-tRNA ligase|1L" 90) "5982|RPL18|YOL120c,9E-37|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein L18A (rp28A)|3P \ 3O" 91) 687.1|RPL25|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:RNA binding (ISS) | F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS) | P:ribosomal large subunit assembly and maintenance (ISS)|ribosomal protein L23a.e|6 92) "7626|CDC33|CDC33|YOL139c,2E-46|C:cytoplasm (ISS) | C:nucleus (ISS) | C:ribosome (ISS)|F:translation initiation factor (ISS) | F:translation initiation factor (ISS)|P:regulation of cell cycle (ISS) | P:translational initiation (ISS) | P:translational initiation (ISS)|mRNA cap-binding protein eIF4E, translation initiation|RD \ RD2" 93) "1601|RPL3|YOR063w,e-123|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS) | P:ribosomal large subunit assembly and maintenance (ISS)|60S large subunit ribosomal protein L3.e|2" 94) "1700|RPS7A|YOR096w,6E-50|C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein S7A|3O" 95) "6314|RPB8|YOR224c,5E-32|C:DNA-directed RNA polymerase I complex (ISS) | C:DNA- directed RNA polymerase II, core (ISS) | C:DNA-directed RNA polymerase III complex (ISS)|F:DNA-directed RNA polymerase I (ISS) | F:DNA-directed RNA polymerase II (ISS) | F:DNA-directed RNA polymerase III (ISS)|P:transcription from Pol I promoter (ISS) | P:transcription from Pol II promoter (ISS) | P:transcription from Pol III promoter (ISS)|16-kDa RNA polymerase subunit (common to polymerases I, II and III)|R" 96) "4796|CAF20|YOR276w,0.0000003|C:mRNA cap complex (ISS)|P:negative regulation of translation ((ISS)) | P:negative regulation of translation (ISS)|binds to eIF-4E, the mRNA cap-binding protein|1J \ 1S" 97) "1199|NOP58|YOR310c,e-119|C:small nuclear ribonucleoprotein complex (ISS) | C:small nucleolar ribonucleoprotein complex (ISS)|F:snoRNA binding (ISS)|P:35S primary transcript processing (ISS) | P:processing of 20S pre-rRNA (ISS) | P:rRNA modification (ISS)|part of small (ribosomal) subunit (SSU) processosome; U3 snoRNP protein|6O" 98) "6785|RPS12|YOR369c,2E-29|C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|acidic ribosomal protein S12|3P" 99) "1154|EGD1|YPL037c,0.000000000000001|C:nascent polypeptide-associated complex (ISS)|F:chaperone (ISS)|P:nascent polypeptide association (ISS)|beta subunit of the nascent-polypeptide-associated complex (NAC)|1X" 100) "4660|RPS6A|YPL090c,3E-51|C:cytosolic small ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein S6A (S10A) (rp9) (YS4)|4N or 4BB" 101) "6541|RPL5|YPL131w,4E-75|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:RNA binding (ISS) | F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS) | P:ribosomal large subunit assembly and maintenance (ISS)|ribosomal protein L5|7F" 102) 6882.1|RPL33A|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein L35a.e.c16|2 103) "3478|NIP7|YPL211w,2E-56|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS) | C:nucleolus (ISS)|F:protein binding (ISS)|P:rRNA processing (ISS) | P:ribosomal large subunit assembly and maintenance (ISS)|nucleolar protein required for 60S ribosome subunit genesis|2U?" 104) "3465|RPL10A|YPL220w,2E-62|C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|ribosomal protein L1A that forms part of the 60S ribosomal subunit|2U?" 105) "7161|SUI3|YPL237w,4E-50|C:ribosome (ISS)|F:translation initiation factor (ISS)|P:translational initiation (ISS)|beta subunit of translation initiation factor eIF-2|7" 106) "3564|RPC40|YPR110c,2E-90|C:DNA-directed RNA polymerase I complex (ISS) | C:DNA- directed RNA polymerase III complex (ISS)|F:DNA-directed RNA polymerase I (ISS) | F:DNA-directed RNA polymerase III (ISS)|P:transcription from Pol I promoter (ISS) | P:transcription from Pol III promoter (ISS)|RNA polymerase III (C) subunit|2U" 107) "3423|TIF3|YPR163c,3E-35|C:ribosome (ISS)|F:translation initiation factor (ISS)|P:translational initiation (ISS)|translation initiation factor eIF4B|6O" 108) "2643|RPO26|YPR187w,1E-34|C:DNA-directed RNA polymerase I complex (ISS) | C:DNA- directed RNA polymerase II, core (ISS) | C:DNA-directed RNA polymerase III complex (ISS)|F:DNA-directed RNA polymerase I (ISS) | F:DNA-directed RNA polymerase II (ISS) | F:DNA-directed RNA polymerase III (ISS)|P:transcription from Pol I promoter (ISS) | P:transcription from Pol II promoter (ISS) | P:transcription from Pol III promoter (ISS)|RNA polymerases I, II, and III subunit|5I" ----------------------------------------------- ----------------------------------------------- Gene set: rRNA (S. cerevisiae) 1) URA7; YBL0410; YBL039C CTP synthase final step in pyrimidine biosynthesis pathway 2) KRR1; YCL059C Protein essential for cell division and spore germination 3) YDR101C; YD8557.10 Protein of unknown function 4) TRM1; YD9727.15; YDR120C N2,N2-dimethylguanine tRNA methyltransferase, required for methylation of G26 of both mitochondrial andcytoplasmic tRNAs 5) YDR165W; YD8358.19 Protein of unknown function 6) YDR324C; D9798.12 Protein with multiple WD40 repeats 7) YDR449C; D9461.34 Protein of unknown function, localized to the nucleus 8) RMT2; D8035.9; YDR465C Putative protein arginine methyltransferase has similarity to human guanidinoacetate N-methyltransferase 9) YDR496C; D9719.2 Protein of unknown function 10) YER006W Nuclear protein of unknown function, has similarity to mouse Mmr1 protein 11) KRE32; SYGP-ORF47; YER126C Nuclear protein of unknown function 12) DBP3; G3210; YGL078C ATP-dependent RNA helicase CA3; member of the DEAD/DEAH box family 13) ROK1; G1651; YGL171W ATP-dependent RNA helicase required for rRNA processing, member of DEAD box family 14) YGR103W; G5933 Nuclear protein of unknown function with similarity to zebrafish pescadillo 15) YGR128C; G6374 Protein with similarity to Haemophilus glutamate-ammonia-ligase adenylyltransferase (glnE) PIR:G64046 16) YGR145W; G6623 Component of NuA3 histone acetyltransferase complex 17) FYV13; G7004; YGR160W Protein of unknown function 18) SDA1; G9101; YGR245C Essential protein required for normal organization of the actin cytoskeleton 19) YGR280C; G9534 Protein of unknown function 20) YHR052W Protein of unknown function 21) RPF1; YHR088W Protein of unknown function, may be involved processing of precursor rRNAs 22) DBP8; YHR169W Protein with similarity to DEAD box family of RNA helicases 23) NMD3; SRC5; YHR170W Protein involved in the nuclear export of 60S ribosomal subunits 24) YHR196W Protein of unknown function 25) YHR197W Component of NuA3 histone acetyltransferase complex 26) YIL127C; YI8277.02 Protein of unknown function 27) YJL122W; J0723 Protein of unknown function 28) RPA34; CST21; J0637; YJL148W RNA polymerase I subunit, not shared with other RNA polymerases 29) MRT4; YKL160; YKL009W Protein involved in mRNA turnover 30) JA2; DHR2; YKL408; YKL078W RNA helicase of DEAH box family, possible pre-mRNA splicing factor 31) LTV1; YKL2; YKL143W Protein required for viability at low temperature 32) EBP2; YKL636; YKL172W Protein involved in pre-rRNA processing and ribosomal subunit assembly 33) TRM2; RNC1; NUC2; (NUD1); YKR056W Uridine methyltransferase that catalyzes the formation of ribothymidine at position 54 in cytoplasmicand mitochondrial tRNA 34) YKR081C; YKR401 Protein of unknown function 35) DRS1; L1345; YLL008W RNA helicase of the DEAD box family involved in rRNA biogenesis 36) YLR002C; L1392 Protein of unknown function 37) YLR009W; L1551 Possible ribosomal protein with similarity to ribosomal protein L24 38) PWP1; L8167.10; YLR196W Periodic tryptophan protein, has WD (WD-40) repeats 39) YLR222C; CST29; L8083.8 Protein of unknown function, overproduction causes chromosome instability and increased mitotic recombination,contains WD (WD-40) repeats 40) DBP9; L9328.3; YLR276C Protein with similarity to DEAD box RNA helicases 41) YLR409C; L8084.22 Protein of unknown function, has WD (WD-40) repeats 42) YML093W Protein of unknown function 43) ERB1; YM9796.02; YMR049C Protein with possible role in ribosome biogenesis, has similarity to mouse Bop1 growth supressor, has one WD(WD-40) domain 44) RSA2; YM9553.07; YMR131C Protein involved in ribosome assembly, member of WD (WD-40) repeat family 45) HAS1; YMR290C RNA helicase of the DEAD/DEAH box family 46) RLP7; N2014; YNL002C Protein with similarity to ribosomal proteins including Rpl7p (Rpl7Ap and Rpl7Bp), involved in processing of precursorrRNAs gene has low codon bias 47) YNL110C; N1954 Protein of unknown function, contains one RNA recognition (RRM) domain 48) KRE33; N1216; N1858; YNL132W Protein of unknown function 49) AAH1; N1208; N1825; YNL141W Adenine deaminase (adenine aminohydrolase), enzyme of the purine salvage pathway has similarity toadenosine deaminases 50) YNL174W; N1669 Protein of unknown function 51) NOP13; N1665; YNL175C Nucleolar protein with similarity to Nsr1p, has two RNA recognition (RRM) domains 52) YNL182C; N1636 Protein of unknown function 53) RPA49; N0880; YNL248C RNA polymerase I third largest subunit 54) KRI1; N0388; YNL308C Protein required for synthesis of 40S ribosomal subunits, binds Krr1p and has weak similarity to Mgm1p 55) BRX1; O1115; YOL077C Protein required for biogenesis of the 60S ribosomal subunit, localized to the nucleolus 56) YOL124C; O0546 Protein of unknown function 57) YOR004W; UNB254; O2521 Protein of unknown function 58) YOR206W; O4843; YOX001 Protein of unknown function 59) YTM1; CST14; O5437W; YOR272W Microtubule-associated protein essential for the G1/S transition, member of WD (WD-40) repeat family 60) NOP4; NOP77; P7102.07; YPL043W Nucleolar protein required for ribosome biogenesis, has 3 canonical RNA recognition (RRM) domains andone degenerate RNA recognition (RRM) domain 61) RPC40; RPC5; P8283.18; YPR110C Shared subunit of RNA polymerases I and III ----------------------------------------------- Gene set: rRNA (C. albicans) 1) "3941|URA7|YBL039c,e-157|C:cytosol (ISS)|F:CTP synthase (ISS) | F:CTP synthase (ISS)|P:phospholipid biosynthesis (ISS) | P:pyrimidine base biosynthesis (ISS)|CTP synthase|5I" 2) "661|KRR1|YCL059c,6E-87|C:nucleolus (ISS)|F:molecular_function unknown (ND)|P:ribosome biogenesis (ISS)|essential for nucleolar ribosomal 18S rRNA processing|1E" 3) "3015|YDR101c,7E-90|conserved hypothetical protein|1SZ" 4) "3265|TRM1 |YDR120c,8E-78|C:mitochondrion (ISS) | C:nuclear outer membrane (ISS)|F:tRNA (guanine-N2-)-methyltransferase (ISS) | F:tRNA (guanine-N2-)-methyltransferase (ISS)|P:tRNA methylation (ISS)|N2,N2-dimethylguanosine-specific tRNA methyltransferase|2U ?" 5) "6477|YDR165w,4E-31|conserved hypothetical protein|7F" 6) "1633|UTP4|YDR324c,e-115|C:small nucleolar ribonucleoprotein complex (ISS)|F:snoRNA binding (ISS)|P:processing of 20S pre-rRNA (ISS) | P:processing of 20S pre-rRNA (ISS)|U3 snoRNP protein|3O" 7) "2330|UTP6|YDR449c,3E-65|C:small nucleolar ribonucleoprotein complex (ISS)|F:snoRNA binding (ISS)|P:processing of 20S pre-rRNA (ISS) | P:processing of 20S pre-rRNA (ISS)|U3 snoRNP protein|1" 8) "920|RMT2|YDR465c,4E-63|P:arginine metabolism (IEA)|arginine methyltransferase|5" 9) "3547|PUF6|YDR496c,e-103|member of the PUF protein family|2U" 10) "2917|NUG1|YER006w,2E-91|C:nucleolus (ISS) | C:nucleus (ISS)|F:molecular_function unknown (ND)|P:biological_process unknown (ND)|GTPase involved in ribosome biogenesis|4H" 11) "7424|NSA2|YER126c,4E-80|C:nucleus (ISS)|F:molecular_function unknown (ND)|P:ribosomal large subunit biogenesis (ISS) | P:ribosomal large subunit biogenesis (ISS)|Killer toxin Resistant | ribosomal biogenesis|3P" 12) "4870|DBP3|YGL078c,e-111|C:nucleolus (ISS)|F:ATP dependent RNA helicase (ISS)|P:35S primary transcript processing (ISS) | P:ribosomal large subunit assembly and maintenance (ISS)|ATP-dependent RNA helicase CA3 of the DEAD/DEAH box family|1J \ 1S" 13) "3756|ROK1|YGL171w,e-111|C:nucleolus (ISS)|F:ATP dependent RNA helicase (ISS)|P:35S primary transcript processing (ISS) | P:mRNA splicing (ISS)|DEAD box RNA helicase|1" 14) "4093|NOP7|YGR103w,e-123|C:nucleolus (ISS) | C:nucleus (ISS)|F:molecular_function unknown (ND)|P:ribosomal large subunit biogenesis (ISS)|pescadillo homolog | nucleolar protein required for rRNA processing|2U" 15) "5436|UTP8|YGR128c,2E-22|C:small nucleolar ribonucleoprotein complex (ISS)|F:snoRNA binding (ISS)|P:processing of 20S pre-rRNA (ISS) | P:processing of 20S pre-rRNA (ISS)|snoRNA binding protein|3" 16) "6686|ENP2|YGR145w,e-146|conserved hypothetical protein|7" 17) "6648|SDA1|YGR245c,e-134|C:nucleus (ISS)|F:molecular_function unknown (ND)|P:actin cytoskeleton organization and biogenesis (ISS) | P:start control point of mitotic cell cycle (ISS)|required for normal organization of the actin cytoskeleton and passage through Start|R" 18) "3831|PXR1|YGR280c,2E-40|PinX1-Related gene G-patch NucleOlar protein | possible telomerase regulator or RNA-binding protein|4F2" 19) "124|CIC1|YHR052w,0.0000000009|C:26S proteasome (ISS) | C:26S proteasome (ISS)|F:protease substrate recruitment factor (ISS) | F:protease substrate recruitment factor (ISS) | F:protease substrate recruitment factor (ISS)|P:protein catabolism (ISS) | P:protein catabolism (ISS) | P:protein catabolism (ISS)|protease substrate recruitment factor|6O" 20) "2667|RPF1|YHR088w,6E-60|C:nucleolus (ISS)|F:molecular_function unknown (ND)|P:ribosomal large subunit assembly and maintenance (ISS)|nucleolar protein involved in rRNA processing|4" 21) "6652|DBP8|YHR169w,e-113|C:nucleolus (ISS) | C:nucleolus (ISS)|F:ATP dependent RNA helicase (ISS) | F:ATP dependent RNA helicase (ISS)|P:35S primary transcript processing (ISS) | P:35S primary transcript processing (ISS)|DEAD box protein ATP-dependent RNA helicase|R" 22) "706|NMD3|YHR170w,e-115|C:cytosol (ISS) | C:cytosolic large ribosomal subunit (sensu Eukarya) (ISS)|F:RNA binding (ISS) | F:protein binding (ISS)|P:ribosomal large subunit assembly and maintenance (ISS)|nonsense mRNA degradation; ribosomal assembly|R" 23) "6862|YHR197w,3E-44|conserved hypothetical protein|4" 24) 1708|hypothetical protein of conserved synteny with related S. cerevisiae protein|3O 25) "7107|YJL122w,0.000002|conserved hypothetical protein|7C \ 7A" 26) "4896|RPA34|YJL148w,0.0000000000009|C:DNA-directed RNA polymerase I complex (ISS)|F:DNA- directed RNA polymerase I (ISS)|P:transcription from Pol I promoter (ISS)|RNA polymerase I subunit|1J \ 1S" 27) "5550|MRT4|YKL009w,1E-65|C:cellular_component unknown (ND)|F:molecular_function unknown (ND)|P:ribosomal large subunit biogenesis (ISS) | P:ribosomal large subunit biogenesis (ISS)|required for mRNA decay|6O" 28) "107|DHR2|YKL078w,e-135|C:nucleolus (ISS)|F:RNA helicase (ISS)|P:ribosome biogenesis (ISS) | P:ribosome biogenesis (ISS)|DEAH-box RNA helicase|6O" 29) "7650|LTV1|YKL143w,0.00000000000001|C:cellular_component unknown (ND)|F:molecular_function unknown (ND)|P:response to stress (ISS)|low-temperature viability protein|RD \ RD2" 30) "4492|EBP2|YKL172w,9E-50|C:nucleolus (ISS)|F:molecular_function unknown (ND)|P:rRNA processing (ISS)|nucleolar protein | required for pre-rRNA processing and ribosomal subunit assembly |2" 31) "3327|TRM2|YKR056w,2E-97|F:tRNA methyltransferase (ISS)|P:tRNA modification (ISS)|tRNA(m5U54)methyltransferase|1SZ" 32) "3553|RPF2|YKR081c,2E-73|C:nucleolus (ISS)|F:molecular_function unknown (ND)|P:ribosomal large subunit assembly and maintenance (ISS)|ribosome large subunit assembly|2U" 33) "7635|DRS1|YLL008w,e-117|C:nucleolus (ISS)|F:ATP dependent RNA helicase (ISS)|P:35S primary transcript processing (ISS) | P:ribosomal large subunit assembly and maintenance (ISS)|ATP dependent RNA helicase|RD \ RD2" 34) "7197|NOC3|YLR002c,3E-85|C:nucleolus (ISS) | C:nucleus (ISS)|P:DNA replication initiation (ISS) | P:rRNA processing (ISS)|nuclear export of pre-ribosomes|7" 35) "4191|RLP24|YLR009w,1E-37|C:cellular_component unknown (ND)|F:molecular_function unknown (ND)|P:ribosomal large subunit biogenesis (ISS) | P:ribosomal large subunit biogenesis (ISS)|similar to ribosomal protein L24.e.B|4N" 36) "4640|PWP1|YLR196w,e-105|beta-transducin superfamily with periodic tryptophan residues|4N or 4BB" 37) "4268|YLR222c,e-152|C:small nucleolar ribonucleoprotein complex (ISS)|F:snoRNA binding (ISS)|P:processing of 20S pre-rRNA (ISS) | P:processing of 20S pre-rRNA (ISS)|conserved hypothetical protein|5M" 38) "3393|DBP9|YLR276c,e-133|C:nucleolus (ISS)|F:ATP dependent RNA helicase (ISS)|P:35S primary transcript processing (ISS) | P:ribosomal large subunit assembly and maintenance (ISS)|dead-box protein 9|6O" 39) "1566|UTP21|YLR409c,0|U3 snoRNP protein | strong similarity to S. pombe beta-transducin|2U" 40) "7552|YML093w,1E-98|C:small nucleolar ribonucleoprotein complex (ISS)|F:snoRNA binding (ISS)|P:processing of 20S pre-rRNA (ISS) | P:processing of 20S pre-rRNA (ISS)|conserved hypothetical protein|RD \ RD2" 41) "1047|ERB1|YMR049c,0|maturation of the 25S and 5.8S ribosomal RNAs|1S" 42) "6355|RSA2|YMR131c,e-114|C:nucleolus (ISS)|F:molecular_function unknown (IEA)|P:ribosome biogenesis (IEA)|involved in the regulation of ribosome biosynthesis|1" 43) "3962|HAS1|YMR290c,e-140|C:nuclear membrane (ISS) | C:nucleolus (ISS)|F:RNA helicase (IEA)|P:biological_process unknown (IEA)|RNA-dependent helicase|5I" 44) "3867|RLP7 |YNL002c,5E-22|C:nucleolus (ISS)|F:rRNA binding (ISS)|P:processing of 27S pre-rRNA (ISS) | P:ribosomal large subunit biogenesis (ISS)|ribosomal-like proteins|R" 45) "7050|NOP15|YNL110c,0.0000000000000002|C:nucleolus (ISS) | C:nucleus (ISS)|F:molecular_function unknown (ND)|P:ribosomal large subunit biogenesis (ISS) | P:ribosomal large subunit biogenesis (ISS)|nucleolar protein 15 | ribosome biogenesis|7C \ 7A" 46) "512|KRE33|YNL132w,0|highly conserved essential protein|RK \ RS" 47) "2251|AAH1|YNL141w,5E-88|C:intracellular (ISS)|F:adenine deaminase (ISS)|P:adenine catabolism (ISS)|adenine aminohydrolase | adenine deaminase|2U" 48) "6766|NOP13|YNL175c,5E-48|C:nucleolus (ISS) | C:nucleoplasm (ISS)|F:RNA binding (ISS)|P:biological_process unknown (ND)|Nucleolar Protein 13|3P" 49) 6234|conserved hypothetical protein|1J 50) "2017|RPA49|YNL248c,3E-80|C:DNA-directed RNA polymerase I complex (ISS)|F:DNA- directed RNA polymerase I (ISS)|P:transcription from Pol I promoter (ISS)|RNA polymerase I alpha subunit|2U" 51) "1609|KRI1|YNL308c,3E-58|C:nucleolus (ISS)|F:molecular_function unknown (ND)|P:ribosome biogenesis (ISS)|Krr1p binding protein|3O" 52) 5232|C:nucleolus (ISS)|F:molecular_function unknown (ND)|P:ribosomal large subunit assembly and maintenance (ISS)|conserved hypothetical protein|1L 53) "5987|YOL124c,7E-99|conserved hypothetical protein|3P \ 3O" 54) "3724|YOR004w,5E-44|processing of 20S pre-rRNA|R" 55) "5850|YOR206w,e-130|C:nucleus (ISS)|F:molecular_function unknown (ND)|P:biological_process unknown (ND)|conserved hypothetical protein|R" 56) "4815|YTM1|YOR272w,3E-98|C:nucleolus (ISS) | C:nucleus (ISS) | C:nucleus (ISS)|F:cytoskeletal protein binding (ISS)|P:cytoskeleton organization and biogenesis (ISS) | P:ribosomal large subunit biogenesis (ISS) | P:ribosomal large subunit biogenesis (ISS)|microtubule-associated protein|1J \ 1S" 57) "5198|NOP4|YPL043w,3E-84|C:nucleolus (ISS)|F:RNA binding (ISS)|P:rRNA processing (ISS)|nucleolar protein|R" 58) "3564|RPC40|YPR110c,2E-90|C:DNA-directed RNA polymerase I complex (ISS) | C:DNA- directed RNA polymerase III complex (ISS)|F:DNA-directed RNA polymerase I (ISS) | F:DNA-directed RNA polymerase III (ISS)|P:transcription from Pol I promoter (ISS) | P:transcription from Pol III promoter (ISS)|RNA polymerase III (C) subunit|2U" ----------------------------------------------- ----------------------------------------------- Gene set: MRP (S. cerevisiae) 1) MRPL16; RML16; YBL0411; YBL038W Mitochondrial ribosomal protein of the large subunit (YmL47 E. coli L16), belongs to the L16 family ofprokaryotic ribosomal proteins 2) MRP21; YBL0702; YBL090W Mitochondrial ribosomal protein of the small subunit 3) CBP6; YBR0916; YBR120C Translational activator of COB mRNA 4) MRPL36; YML36; YBR0918; YBR122C Mitochondrial ribosomal protein of the large subunit 5) MRPS9; YBR1123; YBR146W Mitochondrial ribosomal protein of the small subunit S9, member of prokaryotic ribosomal protein S9 family 6) MBA1; YBR1307; YBR185C Protein required for the assembly of mitochondrial respiratory complexes 7) MRPS5; YBR1704; YBR251W Mitochondrial ribosomal protein of the small subunit,homolog of E. coli ribosomal protein S5 8) MRPL37; YML37; YBR1736A; YBR268W Mitochondrial ribosomal protein of the large subunit 9) MRPL27; YML27; YBR2019; YBR282W Mitochondrial ribosomal protein of the large subunit 10) MRPL32; YML32; YCR041; YCR003W Mitochondrial ribosomal protein of the large subunit 11) RSM10; YD6888.03; D4150; YDR041W Component of the mitochondrial ribosomal small subunit 12) PET100; YD8554.12; D4441; YDR079W Protein required for assembly of cytochrome c oxidase 13) YDR115W; YD9727.10 Probable component of the mitochondrial ribosome, has similarity to prokaryotic L34 ribosomal protein 14) YDR116C; YD9727.11 Probable component of mitochondrial ribosomes, has similarity to prokaryotic ribosomal protein L1 15) RSM24; RSM52; YD9395.08; YDR175C Protein of the mitochondrial ribosomal small subunit 16) MRPL7; YD8419.04; YDR237W Mitochondrial ribosomal protein of the large subunit (YmL5/YmL7), belongs to the L5 family of prokaryoticribosomal proteins 17) YDR316W; D9740.1 Protein of unknown function, has predicted S-adenosylmethionine-dependent methyltransferase motif 18) MRPL35; YML35; D9798.5; YDR322W Mitochondrial ribosomal protein of the large subunit 19) MRPS28; D9651.3; YDR337W Mitochondrial ribosomal protein of the small subunit (E. coli S15) 20) YDR493W; D8035.36 Protein of unknown function 21) YDR494W; D8035.37 Protein of unknown function 22) ACN9; D9719.16; YDR511W Protein required for acetate utilization 23) TTR1; GRX2; TTR D9719.17; YDR513W Glutaredoxin (thioltransferase, glutathione reductase) 24) RSM18; YER050C Component of the mitochondrial ribosomal small subunit 25) PET117; YER058W Protein involved in assembly of cytochrome oxidase 26) YER182W Protein of unknown function 27) YFR011C Protein of unknown function 28) YGL068W; G3277 Putative mitochondrial ribosomal protein, possible homolog of E. coli L7/L12 ribosomal protein 29) YGL069C; G3274 Protein of unknown function questionable ORF 30) RSM23; RSM51; G2856; YGL129C Component of the mitochondrial ribosomal small subunit, required for respiration and mitochondrialmaintenance, putative ATPase 31) YGR021W; G4031 Protein of unknown function, likely involved in mitochondrial protein synthesis 32) MRPL25; YMR26; YML25; G4575; YGR076C Mitochondrial ribosomal protein of the large subunit YMR26 (YmL25) 33) MRP13; G4618; YGR084C Mitochondrial ribosomal protein of the small subunit 34) PHB1; PHB G6390; YGR132C Prohibitin, involved in determination of replicative lifespan member of the prohibitin complex with Phb2p 35) YGR165W; G7050 Protein of unknown function, may be involved in mitochondrial translation 36) CBP4; G7122; YGR174C Ubiquinol-cytochrome c reductase assembly factor essential for assembly and stability of ubiquinol-cytochrome creductase 37) RSM27; RSM55; G7821; YGR215W Protein of the mitochondrial ribosome small subunit 38) YGR219W; ORF113; G8517 Protein of unknown function 39) MRPL9; YML9; ORF269; G8520; YGR220C Mitochondrial ribosomal protein of the large subunit (YmL9 E. coli L3; human MRL3) 40) PHB2; ORF315; G8561; YGR231C Prohibitin, involved in determination of replicative lifespan member of the prohibitin complex with Phb1p 41) YHR116W Protein of unknown function, may be involved in mitochondrial translation 42) MRPL6; YHR147C Mitochondrial ribosomal protein of the large subunit (YmL16), belongs to L6 family of prokaryotic ribosomal proteins 43) MAM33; YIL070C Mitochondrial protein required for normal respiratory growth 44) FMC1; YIL098C Protein involved in production or assembly of mitochondrial cytochromes 45) AYR1; YI8277.05; YIL124W 1-Acyl dihydroxyacetone phosphate reductase 46) YIL157C Protein of unknown function 47) MRPL49; YML49; J0904; YJL096W Mitochondrial ribosomal protein of the large subunit (YmL49) 48) MIA1; J0822; YJL104W Mitochondrial protein with a role in respiration 49) ATP12; J0486; YJL180C F1-ATP synthase assembly protein 50) YJR080C; J1847 Protein of unknown function 51) RSM26; RSM54; J1952; YJR101W Protein of the mitochondrial ribosome small subunit, required for respiratory growth, may have an indirect rolein stress resistance and pseudohyphal growth 52) MRP17; YKL003C Mitochondrial ribosomal protein of the small subunit 53) CYT2; YKL087C Holocytochrome c1 synthase (cytochrome c1 heme lyase) 54) YKL137W Protein required for respiratory growth, for normal distribution of actin patches, and for normal resistance to NaCl and H2O2 55) MRPL31; (YML31); YKL138C Mitochondrial ribosomal protein of the large subunit 56) MRP49; YKL631; YKL167C Mitochondrial ribosomal protein of the large subunit, 57) YKL169C; YKL633 Protein of unknown function questionable ORF 58) MRPL38; YML38; YKL634; YKL170W Mitochondrial ribosomal protein of the large subunit (YmL38) 59) YKL195W Protein of unknown function 60) MRPL13; YK105; YKR006C Mitochondrial ribosomal protein of the large subunit 61) YKR016W Protein possibly involved in respiration 62) YKR065C Protein of unknown function 63) MRPL20; YML20; YKR405; YKR085C Mitochondrial ribosomal protein of the large subunit (YmL20) 64) COX17; L1343; YLL009C Cytoplasmic protein involved in delivery of copper ions to mitochondrial cytochrome oxidase 65) MEF1; L2195; YLR069C Mitochondrial translation elongation factor G, promotes GTP-dependent translocation of nascent chain from A-site toP-site of ribosome 66) QRI5; L8167.17A; YLR204W Protein of unknown function 67) YLR218C; L_F150 Protein of unknown function 68) MRPL39; YML39; YM9571.09; YML009C Mitochondrial ribosomal protein of the large subunit 69) YML030W Protein of unknown function, may be involved in mitochondrial translation 70) COQ5; TCM7; YM8339.09; YML110C; DBI56 Mitochondrial C-methyltransferase of the ubiquinone biosynthetic pathway 71) COX14; M_F70 YM4987.06; YML129C Protein required for assembly of cytochrome oxidase 72) YMR157C; YM8520.06 Protein of unknown function, may be involved in mitochondrial translation 73) YMR158W; YM8520.07 Protein with weak similarity to E. coli ribosomal protein S8 74) YMR188C; YM8010.18 Probable mitochondrial ribosomal protein, has weak similarity to prokaryotic 30S ribosomal protein S17 75) MRPL24; MRP-L14; YML24; YML14; YM9646.05; YMR193W Mitochondrial ribosomal protein of the large subunit (YmL24) 76) MRPL44; YMR44; YM9959.07; YMR225C Mitochondrial ribosomal protein of the large subunit (YmR44) 77) PPA2; IPP2; YM8156.09; YMR267W Inorganic pyrophosphatase, mitochondrial 78) MRP7; MRPL2; N2007; YNL005C Mitochondrial ribosomal protein of the large subunit (YmL2) 79) YNL081C; N2322; YNI1 Putative mitochondrial ribosomal protein of the small subunit, has similarity to ribosomal protein S13 of prokaryotes andplant mitochondria 80) YNL100W; N2190 Protein of unknown function 81) YNL122C; N1901 Protein of unknown function 82) NAM9; MNA6; N1211; N1840; YNL137C Mitochondrial ribosomal protein of the small subunit member of E. coli S4 superfamily 83) YNL177C; N1657 Protein of unknown function, may be involved in mitochondrial translation 84) MRPL17; YML30; YML17; N0864; YNL252C Mitochondrial ribosomal protein of the large subunit 85) MRPL10; N0580; YNL284C Mitochondrial ribosomal protein of the large subunit (YmL10), member of the L15 family of prokaryotic ribosomalproteins 86) YNL306W; YMS18; MRPS-18; YNL0397; N0397 Mitochondrial ribosomal protein of the small subunit (YmS18), has similarity to bacterial andchloroplast ribosomal protein S11 87) ATP11; N0357; YNL315C F1-ATP synthase assembly protein 88) YNR022C; N3220 Protein of unknown function 89) YOL071W; O1145 Protein of unknown function 90) HSP10; CPN10; OR26.10; O2634; YOR020C Mitochondrial chaperonin that cooperates with Hsp60p, counterpart of E. coli GroES 91) MRPL23; YML23; O3530; YOR150W Mitochondrial ribosomal protein of the large subunit 92) PET123; O3557; YOR158W Mitochondrial ribosomal protein of the small subunit 93) TUF1; TUFM O4741; YOR187W Translation elongation factor Tu, mitochondrial 94) YOR215C; YOR50-5; O5005 Protein of unknown function 95) YOR286W; O5489W Protein with similarity to Drosophila melanogaster heat shock protein 67B2 96) YDC1; LPG21; YPL087W Alkaline ceramidase with specificity for dihydroceramide 97) MRP51; LPH9; YPL118W Mitochondrial ribosomal protein of the small subunit 98) YPR099C; P8283.13A Protein of unknown function 99) YPR100W; P8283.12 Protein of unknown function 100) MRP2; P9325.7; YPR166C Mitochondrial ribosomal protein of the small subunit ----------------------------------------------- Gene set: MRP (C. albicans) 1) 2019|MRPL16|C:mitochondrial large ribosomal subunit (ISS)|F:peptidyltransferase (ISS) | F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|mitochondrial ribosome large subunit protein L16|2U 2) "2852|MRP21|YBL090w,0.0000002|C:mitochondrial small ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:translational initiation (ISS)|mitochondrial ribosome small subunit component|R" 3) 2201|CBP6|C:mitochondrion (ISS)|F:molecular_function unknown (ISS)|P:protein biosynthesis (ISS)|pre-mRNA processing protein | translational activator|2U 4) "3205|MRPL36|YBR122c,0.0000005|C:mitochondrial large ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|mitochondrial ribosome LSU protein L36|5M" 5) "5230|MRPS9|MRPS9|YBR146w,1E-45|C:mitochondrial small ribosomal subunit (ISS) | C:mitochondrial small ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS) | F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|40S ribosomal protein S9, mitochondrial PRECURSOR|1L" 6) "7386|MBA1|YBR185c,0.0000000000001|C:mitochondrial inner membrane (ISS)|F:molecular_function unknown (ND)|P:aerobic respiration (ISS) | P:inner mitochondrial membrane organization and biogenesis (ISS)|assembly of mitochondrial respiratory complexes|3P" 7) "989|MRPS5|YBR251w,7E-38|C:mitochondrial ribosome (ISS) | C:mitochondrial small ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS) | F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|mitochondrial ribosomal protein S5|1E or 1L" 8) "755|MRPL37|YBR268w,0.000000003|C:mitochondrial large ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|mitochondrial ribosomal protein L37|1" 9) "3064|MRPL27|YBR282w,2E-19|C:mitochondrial large ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|mitochondrial ribosome protein L27|1SZ" 10) "549|MRPL32|YCR003w,0.000000000002|C:mitochondrial large ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|mitochondrial ribosomal large subunit protein|RK \ RS" 11) "6752|RSM10|YDR041w,4E-19|C:mitochondrial small ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|mitochondrial ribosome small subunit component|3P" 12) "4862.2|PET100|YAR035w,2E-92|C:mitochondrial inner membrane (ISS)|F:chaperone (ISS)|P:aerobic respiration (ISS) | P:cytochrome c oxidase biogenesis (ISS)|cytochrome c oxidase-specific assembly factor|1J \ 1S" 13) 961.2|C:mitochondrial large ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|similarity to bacterial ribosomal L34 proteins|5M 14) "5698|RPL1|YDR116c,6E-22|C:mitochondrial large ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:aerobic respiration (IEP) | P:aerobic respiration (ISS) | P:meiosis (IEP)|ribosomal protein L1|5" 15) "3022|S24|YDR175c,1E-32|C:mitochondrial small ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:aerobic respiration (IEP) | P:aerobic respiration (ISS) | P:protein biosynthesis (ISS)|mitochondrial ribosome small subunit component|1SZ" 16) "2214|MRPL7|YDR237w,9E-52|C:mitochondrial large ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|mitochondrial ribosomal protein|2U" 17) "1300|YDR316w,2E-53|conserved hypothtical protein|4N" 18) "863|MRPL35|YDR322w,4E-51|C:mitochondrial large ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|ribosomal protein of the large subunit, mitochondrial|2U" 19) "2520|MRPS28|YDR337w,1E-30|C:mitochondrial small ribosomal subunit (ISS) | C:mitochondrial small ribosomal subunit (ISS)|F:RNA binding (ISS) | F:structural constituent of ribosome (ISS) | F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS) | P:ribosomal small subunit assembly and maintenance (ISS)|mitochondrial ribosomal small subunit protein|RMZ" 20) "5433|YDR493w,0.000000003|conserved hypothetical protein|3" 21) "6328|ACN9|YDR511w,4E-21|C:mitochondrial intermembrane space (ISS)|F:molecular_function unknown (ND)|P:carbon utilization by utilization of organic compounds (ISS) | P:gluconeogenesis (ISS)|conserved hypothetical protein|6O" 22) "6059|TTR2|YDR513w,0.0000000000000006|C:cellular_component unknown (ND)|F:thiol-disulfide exchange intermediate (ISS) | F:thiol-disulfide exchange intermediate (ISS)|P:regulation of redox homeostasis (ISS) | P:regulation of redox homeostasis (ISS) | P:response to oxidative stress (ISS)|glutaredoxin|1S" 23) 6225.1|PET117|C:mitochondrial inner membrane (ISS)|F:molecular_function unknown (ISS)|P:cytochrome c oxidase biogenesis (ISS)|cytochrome c oxidase assembly factor|1J 24) "3963|YER182w,0.0000000000006|conserved hypothetical protein|5I" 25) 6062.3|conserved hypothetical protein|1S 26) "2275|RPL12B|YGL068w,5E-24|60S ribosomal protein L7/L12|2U" 27) "3480|RSM23|YGL129c,1E-21|C:mitochondrial small ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|ATPase (putative)| mitochondrial ribosome small subunit component|2U?" 28) "805|YGR021w,5E-19|conserved hypothetical protein|2U" 29) "7675|MRPL25|YGR076c,0.0000000000000003|C:mitochondrial large ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|mitochondrial ribosomal protein MRPL25|RD \ RD2" 30) "357|PHB1|C:mitochondrion (ISS)|F:molecular_function unknown (ND)|P:cell aging (ISS) | P:proteolysis and peptidolysis (ISS) | P:proteolysis and peptidolysis (ISS)|prohibitin, antiproliferative protein|3O" 31) "3559|YGR165w,0.00000000004|conserved hypothetical protein|2U" 32) "392|CBP4|YGR174c,1E-21|C:mitochondrial membrane (ISS)|F:molecular_function unknown (ISS)|P:protein complex assembly (ISS)|ubiquinol-cytochrome c reductase assembly factor|1J" 33) "3297|YGR215w,0.0000004|C:mitochondrial small ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|concerved hypothetical protein|1SZ" 34) "7485|MRPL9|YGR220c,1E-27|C:mitochondrial large ribosomal subunit (ISS)|F:peptidyltransferase (ISS) | F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:ribosomal large subunit assembly and maintenance (ISS)|mitochondrial ribosomal protein of the large subunit|RM" 35) "5973|PHB2|YGR231c,8E-72|C:mitochondrion (ISS)|F:molecular_function unknown (ND)|P:cell aging (ISS) | P:proteolysis and peptidolysis (ISS) | P:proteolysis and peptidolysis (ISS)|mitochondrial prohibitin|3P \ 3O" 36) "3244|YHR116w,0.00000000000001|C:cellular_component unknown (ND)|F:molecular_function unknown (ND)|P:aerobic respiration (IEP) | P:aerobic respiration (ISS)|conserved hypothetical protein|2U ?" 37) "7486|MRPL6|YHR147c,2E-30|C:mitochondrial large ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|ribosomal protein L6 precursor, mitochondrial|RM" 38) "7187|MAM33|YIL070c,8E-23|C:mitochondrial matrix (ISS)|F:molecular_function unknown (ND)|P:aerobic respiration (ISS)|mitochondrial acidic matrix protein|7" 39) "6167|AYR1|YIL124w,1E-56|C:cytoplasm (ISS) | C:endoplasmic reticulum (ISS) | C:lipid particle (ISS)|F:acylglycerone-phosphate reductase (ISS)|P:phosphatidic acid biosynthesis (ISS)|1-Acyl dihydroxyacetone phosphate reductase|RM \ S" 40) "5296|YIL157c,2E-19|conserved hypothetical protein|4" 41) "5161|MRPL49|YJL096w,0.0000000000004|C:mitochondrial large ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|mitochondrial ribosomal protein of the large subunit|7" 42) "7222|YJL104w,0.000000000002|conserved hypothetical protein|1S" 43) "3686|ATP12|YJL180c,2E-41|C:mitochondrial matrix (ISS)|F:chaperone (ISS)|P:protein complex assembly (ISS) | P:protein complex assembly (ISS)|F1-ATP synthase assembly protein|1SZ" 44) "3154|YJR080c,0.008|hypothetical protein|3" 45) 3938|C:mitochondrial small ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|Mn-superoxide dismutase|5I 46) "947|MRP17|YKL003c,4E-21|C:mitochondrial small ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|mitochondrial ribosomal protein |5" 47) "4578|CYT2|YKL087c,6E-40|C:mitochondrion (ISS) | C:mitochondrion (ISS)|F:holocytochrome c synthase (ISS) | F:holocytochrome c synthase (ISS)|P:cytochrome c-heme linkage (ISS) | P:cytochrome c-heme linkage (ISS)|cytochrome c1 heme lyase|4N or 4BB" 48) "1483|YKL137w,0.00002|hypothetical protein|2U" 49) "1485|MRPL31|YML31|YKL138c,0.0000000000009|C:mitochondrial large ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|mitochondrial ribosomal protein|2U" 50) "5684|MRPL14|YKL170w,8E-23|C:mitochondrial large ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|mitochondrial ribosomal protein L14|5" 51) "2977|YKL195w,4E-28|conserved hypothetical protein|1SZ" 52) "4396|FMP13|YCR051w,0.000000000000000001|mitochondrial protein|R" 53) "240|YKR065c,1E-27|conserved hypothetical membrane protein|3O" 54) 2006.1|COX17|C:cytosol (ISS) | C:mitochondrial intermembrane space (ISS)|F:intracellular copper transporter (ISS) | F:intracellular copper transporter (ISS)|P:cytochrome c oxidase biogenesis (ISS) | P:intracellular copper delivery (ISS) | P:intracellular copper delivery (ISS)|cytochrome c oxidase copper chaperone|2U 55) "4932|MEF1|YLR069c,0|C:mitochondrion (ISS)|F:translation elongation factor (ISS) | F:translation elongation factor (ISS)|P:translational elongation (ISS) | P:translational elongation (ISS)|mitochondrial translation elongation factor|1L" 56) "1114|YML030w,0.000000000000000006|conserved hypothetical protein|5" 57) "3577|COQ5|YML110c,8E-67|C:mitochondrion (ISS)|F:ubiquinone biosynthesis methyltransferase (ISS) | F:ubiquinone biosynthesis methyltransferase (ISS)|P:aerobic respiration (ISS) | P:ubiquinone metabolism (ISS)|mitochondrial C- methyltransferase | co-enzyme Q deficient|2U" 58) "1546|YMR157c,0.0006|conserved hypothetical protein|2U" 59) "1545|MRPS8|YMR158w,1E-28|mitochondrial ribosome protein, small subunit|2U" 60) "4176|MRPS17|YMR188c,2E-25|C:mitochondrial small ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:aerobic respiration (IEP) | P:aerobic respiration (ISS)|mitochondrial ribosomal protein of the small subunit|4N" 61) "828|MRPL24|YMR193w,0.00000000000000007|C:mitochondrial large ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|mitochondrial ribosomal protein|2U" 62) 639.1|MRPL44|C:mitochondrial large ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|mitochondrial large ribosomal subunit protein|R 63) "4807|PPA2|YMR267w,5E-58|C:mitochondrion (ISS) | C:mitochondrion (ISS)|F:inorganic diphosphatase (ISS) | F:inorganic diphosphatase (ISS)|P:respiratory gaseous exchange (ISS)|mitochondrial inorganic pyrophosphatase|1J \ 1S" 64) "7203|MRP7|YNL005c,5E-36|C:mitochondrial large ribosomal subunit (ISS)|F:peptidyltransferase (ISS) | F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|mitochondrial large ribosomal subunit|7" 65) "6406|SWS2|YNL081c,0.000000000000000001|putative mitochondrial ribosomal protein|RS or RU" 66) "498|NAM9|YNL137c,6E-73|C:mitochondrial small ribosomal subunit (ISS) | C:mitochondrial small ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS) | F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|mitochondrial S4 ribosomal protein|RK \ RS" 67) "3367|YNL177c,4E-34|C:mitochondrial large ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:aerobic respiration (IEP) | P:aerobic respiration (ISS)|conserved hypothetical protein|4O?" 68) "585|MRPL17|YNL252c,1E-41|C:mitochondrial large ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|mitochondrial ribosomal protein of the large subunit|5" 69) "3532|MRPL10|YNL284c,1E-45|C:mitochondrial large ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|mitochondrial ribosomal protein|2U" 70) "688|MRPS18|YNL306w,9E-28|C:mitochondrial small ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS) | F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS)|mitochondrial ribosomal small subunit protein|6" 71) "6916|ATP11|YNL315c,1E-36|C:mitochondrial matrix (ISS)|F:chaperone (ISS)|P:protein complex assembly (ISS) | P:protein complex assembly (ISS)|F1F0-ATPase complex assembly protein|7" 72) "4727|EMI5|YOL071w,1E-24|Early Meiotic Induction|1J \ 1S" 73) 7215.3|HSP10|C:mitochondrial matrix (ISS)|F:chaperone (ISS)|P:protein folding (ISS)|10 kDa mitochondrial heat shock chaperonin|1S 74) 3348|MRPL23|C:mitochondrial large ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:ribosomal large subunit assembly and maintenance (ISS)|mitochondrial ribosomal protein L23|1SZ 75) "4204|PET123|YOR158w,2E-19|C:mitochondrial small ribosomal subunit (ISS) | C:mitochondrial small ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS) | F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|mitochondrial ribosomal protein of small subunit|6O" 76) "6047|TUF1|YOR187w,e-105|C:mitochondrial matrix (ISS) | C:mitochondrial ribosome (ISS)|F:translation elongation factor (ISS)|P:translational elongation ((ISS))|mitochondrial translation elongation factor TU|1S" 77) "2363|YOR286w,0.000000000000000002|putative heat shock protein|R" 78) "3104|YDC1|YPL087w,3E-54|P:sphingolipid metabolism (IEA)|alkaline dihydroceramidase|4H" 79) "185|MRP51|YPL118w,0.000000000000009|C:mitochondrial small ribosomal subunit (ISS) | C:mitochondrial small ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS) | F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS) | P:translational initiation (ISS)|mitochondrial ribosome small subunit component|2U" 80) "5279|YPR100w,0.0000000000000006|conserved hypothetical protein|1L" 81) "4023|MRP2|YPR166c,8E-20|C:mitochondrial small ribosomal subunit (ISS) | C:mitochondrial small ribosomal subunit (ISS)|F:structural constituent of ribosome (ISS) | F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|mitochondrial ribosomal small subunit protein|5I" ----------------------------------------------- ----------------------------------------------- Gene set: STR (S. cerevisiae) 1) YBL064C; PRX1; YBL0503; MTP1; mTPx YBL0524 Mitochondrial thiol peroxidase 2) AUT7; APG8; CVT5; YBL0732; YBL078C Protein that mediates attachment of autophagosomes to microtubules in combination with Aut2p, alsorequired for sporulation 3) UGA2; UGA5; YBR0112; YBR006W Succinate semialdehyde dehydrogenase 4) YBR026C; YBR0310; (MRF1) Nuclear protein essential for mitochondrial respiratory function, binds preferentially to single-stranded coresequence of ARS DNA 5) YBR052C; YBR0505 Protein with similarity to Ycp4p, S. pombe obr1, and E. coli trp repressor binding protein 6) YBR053C; YBR0506 Protein with similarity to rat calcium-binding protein regucalcin and rat senescence marker protein 30 7) YBR056W; YBR0510 Protein with similarity to glucan-1,3-beta-glucosidase (exo-1,3-beta-glucanase) 8) HSP26; YBR0714; YBR072W Heat shock protein of 26 kDa, expressed during entry to stationary phase and induced by osmostress 9) TPS1; CIF1; FDP1; BYP1; GGS1; GLC6; TSS1; YBR0922; YBR126C Trehalose-6-phosphate synthase, component of trehalose-6-phosphatesynthase/phosphatase complex 10) YBR139W; YBR1015 Protein with similarity to serine-type carboxypeptidases 11) ARA1; YBR1127; YBR149W Subunit of NADP+-dependent D-arabinose dehydrogenase 12) SSE2; YBR1221; YBR169C Heat shock protein of the HSP70 family, present at low abundance at 23 deg but greatly induced after shift to 37 deg 13) YPC1; YBR1305; YBR183W Alkaline ceramidase 14) YBR230C; YBR1527 Protein of unknown function 15) GRX1; YCL035C Putative glutaredoxin, has similarity to thioltransferase Ttr1p 16) GLK1; YCL312; YCL040W Glucokinase, specific for aldohexoses 17) YCL042W Protein of unknown function 18) GPM2; D2835; YDL021W Phosphoglycerate mutase, with similarity to Gpm1p and Gpm3p 19) YDL027C; D2800 Protein of unknown function 20) YDL072C; D2492 Protein of unknown function 21) YDL110C; D2320 Protein of unknown function 22) YDL124W; D2240 Protein of unknown function 23) YDL204W; D1062 Protein of unknown function 24) NTH1; NTH YD8119.07; D2955; YDR001C Neutral trehalase 25) PST2; D3422; YD9673.02; YDR032C Protein with similarity to Ycp4p and S. pombe OBR1 brefeldin A resistance protein 26) YDR070C; YD8554.03; D4275 Protein of unknown function 27) TPS2; HOG2; PFK3; D4416; YD8554.07; YDR074W Trehalose-6-phosphate phosphatase, component of the trehalose-6-phosphatasesynthase/phosphatase complex 28) HSP42; YD9395.04; YDR171W Heat shock protein with similarity to Hsp26p, involved in restoration of the cytoskeleton during mild stress 29) SDH4; YD9395.11; YDR178W Membrane anchor subunit in the succinate dehydrogenase complex 30) GGA1; D9476.2; YDR358W Protein involved in trafficking of proteins between the trans-Golgi network and the vacuole 31) YDR391C; D9509.11 Protein of unknown function 32) YDR453C; D9461.38; cTPxII Cytoplasmic thiol peroxidase 33) TTR1; GRX2; TTR D9719.17; YDR513W Glutaredoxin (thioltransferase, glutathione reductase) 34) YDR516C; D9719.21 Protein with similarity to Glk1p 35) YDR533C; D9719.36 Protein of unknown function 36) GLC3; YEL011W alpha-1,4-Glucan branching enzyme 37) UBC8; GID3; YEL012W Ubiquitin-conjugating enzyme involved in the catabolite degradation of fructose-1,6-bisphosphate 38) YER053C Member of the mitochondrial carrier (MCF) family of membrane transporters, has similarity to C. elegans mitochondrial phosphate carrierprotein 39) YER067W Protein of unknown function 40) YER079W Protein of unknown function, may be involved in signal transduction 41) SPI1; YER150W Protein induced in stationary phase, has similarity to Sed1p 42) HSP12; GLP1; YFL014W Heat shock protein of 12 kDa, induced by heat, osmotic stress, oxidative stress and in stationary phase 43) HXK1; HKA YFR053C Hexokinase I, converts hexoses to hexose phosphates in glycolysis repressed by glucose 44) PMC1; G3749; YGL006W Vacuolar Ca2+-transporting P-type ATPase, member of the cation transporting (E1-E2) P-type ATPase superfamily,functions to pump Ca2+ into the vacuole 45) PNC1; G3629; YGL037C Pyrazinamidase and nicotinamidase 46) YGL121C; G2913 Protein of unknown function 47) AMS1; G1861; YGL156W alpha-Mannosidase, hydrolyzes terminal non-reducing alpha-D-mannose residues from alpha-D-mannosides 48) STF2; G3858; YGR008C ATPase stabilizing factor, binds to F0-ATPase facilitates binding of inhibitor and 9 kDa protein to F1-ATPase 49) UGA1; G4027; YGR019W 4-Aminobutyrate aminotransferase 50) YGR043C; G4301 Protein of unknown function, may be involved in signal transduction has strong similarity to Tal1p 51) CTT1; G4628; YGR088W Catalase T (cytosolic) 52) YGR111W; G6145 Protein with similarity to southern house mosquito carboxylesterase PIR:S53372 53) YGR149W; G6639 Protein with similarity to hypothetical protein A-288 54) XKS1; G7584; YGR194C Xylulokinase, required for growth on D-xylulose 55) SOL4; G9125; YGR248W Possible 6-phosphogluconolactonase 56) YHL021C Protein of unknown function 57) YHR087W Protein of unknown function 58) GRE3; H8263.12; YHR104W Aldose reductase with NADPH specificity induced by osmotic stress 59) YHR138C Protein possibly involved in vacuolar fusion, has similarity to Pbi2p, which is a protease B inhibitor 60) COX5B; YIL111W Cytochrome c oxidase chain Vb, expressed under anaerobic conditions 61) AYR1; YI8277.05; YIL124W 1-Acyl dihydroxyacetone phosphate reductase 62) OM45; YIL136W Protein of the outer mitochondrial membrane 63) HYR1; GPX3; YIR037W Glutathione peroxidase involved in oxidative stress response 64) GTT1; YIR038C Glutathione transferase 65) MPM1; HRE252; J1111; YJL066C Protein of unknown function 66) FBP26; J0575; YJL155C Fructose-2,6-bisphosphatase 67) YJL161W; J0552 Protein of unknown function 68) YJL163C; J0544 Protein of unknown function 69) TPK1; SRA3; PKA1; PK25; J0541; YJL164C Catalytic subunit of cAMP-dependent protein kinase 1, protein kinase A or PKA 70) YJR008W; YJR83.9; J1431 Protein of unknown function 71) YJR096W; J1926 Protein with similarity to aldolase reductase 72) GPX1; YKL026C Glutathione peroxidase 73) UGP1; YKL035W; YKL248 UDP-glucose pyrophosphorylase (UTP-glucose-1-P uridylyltransferase) 74) YET1; YKL331; YKL065C Transmembrane protein of the endoplasmic reticulum 75) YNK1; YNK NDK1; YKL333; YKL067W Nucleoside diphosphate kinase, responsible for synthesis of all nucleoside triphosphates except ATP 76) YKL091C; (SFH1) Protein with similarity to Sec14p 77) LAP4; APE1; API YSC1; YKL455; YKL103C Aminopeptidase I (yscI, API) of the vacuole 78) MRP8; YKL3; YKL142W Mitochondrial ribosomal protein of the small subunit 79) MCR1; YKL605; YKL150W NADH-cytochrome b5 reductase 80) YKL151C; YKL606 Protein of unknown function 81) SDS22; EGP1; YKL193C Regulatory subunit for Glc7p type I protein serine/threonine phosphatase with an essential function in late mitosis 82) TOS5; YK111; YKR011C Protein of unknown function 83) ECM4; YKR076W Protein possibly involved in cell wall structure or biosynthesis 84) HSP104; L0948; YLL026W Heat shock protein required for induced thermotolerance and for resolubilizing aggregates of denatured proteins,important for the [psi-] to [PSI+] prion conversion 85) UBI4; SCD2; L0904; YLL039C Ubiquitin polyprotein, mature ubiquitin is cleaved from polyubiquitin (Ubi4p) or from fusions with ribosomalproteins Rps31p, Rpl40Ap, or Rpl40Bp 86) YLR080W; L9449.7; L2365 Protein with similarity to Emp47p 87) YLR149C; L9634.7; L3317 Protein of unknown function 88) TFS1; DKA1; (NSP1); L9470.19; YLR178C CDC25-dependent nutrient- and ammonia-response cell cycle regulator, binds to and inhibits Prc1p(carboxypeptidase Y) 89) YLR251W; L9672.3 Protein with similarity to mouse MPV17 protein 90) YLR252W Protein of unknown function 91) GSY2; L8479.8; YLR258W UDP-glucose-starch glucosyltransferase (glycogen synthetase) isoform 2 92) YLR270W; L8479.2 Protein of unknown function 93) YLR327C; L8543.1 Protein with strong similarity to Stf2p 94) YLR345W; L8300.3 Protein with similarity to rat fructose-2,6-bisphosphatase 95) YLR356W; L9638.2 Protein with similarity to Scm4p, possible Cdc4p-interacting protein 96) GLO1; YM9571.15; YML004C Glyoxalase I, catalyzes condensation of hemimercaptal adduct of methylglyoxal with glutathione to formS-D-lactoylglutathione 97) TSL1; YML100W Component of the trehalose-6-phosphate synthase/phosphatase complex alternate third subunit with Tps3p 98) MSC1; YM4987.07; YML128C Protein of unknown function that affects meiotic homologous chromatid recombination 99) YMR090W; YM9582.15 Protein with similarity to malate dehydrogenases 100) PGM2; GAL5; YM9718.04; YMR105C Phosphoglucomutase major isozyme, interconverts Glc-1-P and Glc-6-P 101) YMR110C; YM9718.09 Protein with similarity to aldehyde dehydrogenases 102) RIM11; MDS1; GSK3; YM9375.08; YMR139W Member of the GSK-3 sub-family of protein kinases (which includes Mck1p, Rim11p, Mrk1p, andYOL128Cp), required for induction of IME2 by Ime1p 103) ALD3; YM8520.18; YMR169C Cytoplasmic, stress inducible aldehyde dehydrogenase, probable isoform of Ald2p 104) ALD2; (ALD5); YM8520.19; YMR170C Aldehyde dehydrogenase (NAD(P)+), likely cytosolic 105) YMR196W; YM9646.09 Protein of unknown function 106) VTI1; YM9646.10; YMR197C Synaptobrevin (v-SNARE) homolog, has an essential role at the cis-Golgi stage and a non-essential role at the Golgito prevacuole stage 107) GAD1; YM9920.04; YMR250W Glutamate decarboxylase 108) PRC1; LBC1; SSU7; CPY YMR297W Carboxypeptidase Y (CPY/yscY), a serine protease 109) YMR315W; YM9924.07 Protein of unknown function 110) PBI2; N2844; YNL015W Protease B (yscB or Prb1p) inhibitor 2 (I2B), has activity related to vacuolar fusion that is not related to protease activity 111) YNL115C; N1929 Protein of unknown function 112) YGP1; N1731; YNL160W Secreted glycoprotein produced in response to nutrient limitation 113) YNL200C; N1370 Protein of unknown function 114) YNL274C; N0631 Potential alpha-ketoisocaproate reductase 115) YNL305C; YNL0405; N0405 Protein with similarity to Aspergillus nidulans negative-acting regulatory protein qutR and Drosophila melanogasterN-methyl-D-aspartate receptor-associated protein 116) CIT1; GLU3; N2019; YNR001C Citrate synthase, mitochondrial, converts acetyl-CoA and oxaloacetate into citrate plus CoA 117) YOL048C; O1292 Protein of unknown function 118) YOL071W; O1145 Protein of unknown function 119) YOL082W; YOL0950; O0980 Protein of unknown function 120) YOL083W; O0957 Protein of unknown function 121) YOL153C Protein of unknown function, has strong similarity to the carboxypeptidase Cps1p 122) YOR052C; YOR29-03; O2796 Protein of unknown function 123) GCY1; GCY O31567; YOR3269; O3269; YOR120W Galactose-induced protein with strong similarity to crystallin protein of vertebrate eye lens 124) YOR173W; O3625 Protein of unknown function 125) YOR215C; YOR50-5; O5005 Protein of unknown function 126) YOR220W; YOR50-10; O5010; O5050 Protein of unknown function 127) YOR285W; O5486W Protein with similarity to Drosophila melanogaster heat shock protein 67B2 128) YOR289W; O5498W Protein of unknown function 129) ALD4; ALD7; O6730; YOR374W Mitochondrial aldehyde dehydrogenase 130) YPL004C; YP8132.09; LPA13 Protein with weak similarity to tropomyosin 131) YDC1; LPG21; YPL087W Alkaline ceramidase with specificity for dihydroceramide 132) RNY1; LPH4; YPL123C Ribonuclease of the ribonuclease T2 family 133) PEP4; PRA1; PHO9; P2585; YPL154C Proteinase A (PrA/yscA/saccharopepsin) aspartyl protease required for activation of various degradativeenzymes 134) YPL165C; P2545 Protein of unknown function 135) YPL196W; P1905 Protein of unknown function 136) TPK2; PKA2; PKA3; YKR1; P1855; YPL203W Catalytic subunit of cAMP-dependent protein kinase 2, protein kinase A or PKA 137) USV1; P1421; YPL230W Putative finger transcripton factor, has a two tandem C2H2-type zinc fingers 138) GPH1; P9584.1; YPR160W Glycogen phosphorylase, releases alpha-D-glucose-1-phosphate from glycogen 139) GDB1; P9705.2; YPR184W Glycogen debranching enzyme (4-alpha-glucanotransferase or oligo-1, 4 - 1, 4-glucantransferase) ----------------------------------------------- Gene set: STR (C. albicans) 1) "5180|PRX1|YBL064c,3E-47|C:mitochondrion (ISS) | C:mitochondrion (ISS)|F:thioredoxin peroxidase (ISS) | F:thioredoxin peroxidase (ISS) | F:thioredoxin peroxidase (ISS)|P:regulation of redox homeostasis (ISS) | P:regulation of redox homeostasis (ISS)|regulation of redox homeostasis|7" 2) "345|UGA2|YBR006w,e-109|C:cellular_component unknown (ISS)|F:succinate- semialdehyde dehydrogenase (NAD(P)+) (ISS)|P:glutamate catabolism (ISS)|succinate semialdehyde dehydrogenase|3O" 3) "5450|ETR1|YBR026c,2E-41|C:mitochondria (ISS)|P:respiratory gaseous exchange (ISS)|2-enoyl thioester reductase|3" 4) "2722|CGR1|CGR1|YBR053c,0.000000004|putatively involved in growth regulation|4" 5) "7214|YBR056w,4E-69|glucan 1,3-beta-glucosidase|1S" 6) "6640|TPS1|TPS1|YBR126c,e-143|C:alpha, alpha-trehalose-phosphate synthase complex (UDP-forming) (ISS) | C:alpha, alpha-trehalose-phosphate synthase complex (UDP-forming) ((ISS)) | C:alpha, alpha- trehalose-phosphate synthase complex (UDP-forming) (ISS) | C:alpha, alpha-trehalose-phosphate synthase complex (UDP- forming) (ISS) | C:alpha, alpha-trehalose-phosphate synthase complex (UDP-forming) (ISS) | C:cytoplasm (ISS)|F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) (ISS) | F:alpha,alpha-trehalose-phosphate synthase (UDP- forming) (ISS)|P:carbohydrate metabolism (ISS) | P:carbohydrate metabolism (ISS) | P:response to stress (ISS) | P:response to stress ((ISS)) | P:response to stress (ISS)|trehalose-6-phosphate synthase|R" 7) "2172|ARA1|YBR149w,5E-56|C:cellular_component unknown (ND)|F:D-arabinose 1- dehydrogenase [NAD(P)] (ISS)|P:carbohydrate metabolism (ISS) | P:carbohydrate metabolism (ISS)|D-arabinose dehydrogenase|2U" 8) 734|GLK1|C:cytosol (ISS)|F:glucokinase (ISS)|P:carbohydrate metabolism (ISS)|aldohexose specific glucokinase|1 9) "1564|YDL072c,3E-24|conserved hypothetical membrane protein|2U" 10) "1340|YDL124w,8E-42|aldose reductase|7" 11) "7479|NTH1|NTH1|YDR001c,e-165|C:cellular_component unknown (ND)|F:alpha,alpha- trehalase (ISS)|P:response to stress (ISS) | P:trehalose catabolism (ISS)|neutral trehalase (alpha,alpha-trehalase)|RM" 12) "3038|TPS2|YDR074w,0|C:alpha, alpha- trehalose-phosphate synthase complex (UDP-forming) (ISS)|F:trehalose phosphatase (ISS)|threalose-6-phosphate phosphatase|1SZ" 13) "4468|SDH4|C:mitochondrial matrix (ISS) | C:mitochondrial matrix (ISS) | C:succinate dehydrogenase complex (sensu Eukarya) (ISS)|F:succinate dehydrogenase (ISS)|P:oxidative phosphorylation, succinate to ubiquinone (ISS) | P:succinate metabolism (ISS) | P:tricarboxylic acid cycle (ISS)|succinate dehydrogenase membrane anchor subunit|1" 14) "6059|TTR2|YDR513w,0.0000000000000006|C:cellular_component unknown (ND)|F:thiol-disulfide exchange intermediate (ISS) | F:thiol-disulfide exchange intermediate (ISS)|P:regulation of redox homeostasis (ISS) | P:regulation of redox homeostasis (ISS) | P:response to oxidative stress (ISS)|glutaredoxin|1S" 15) "251|YDR533c,2E-58|conserved hypothetical protein|3O" 16) "5622|GLC3|YEL011w,e-162|C:cellular_component unknown (ND)|F:1,4-alpha- glucan branching enzyme ((ISS)) | F:1,4-alpha-glucan branching enzyme (ISS)|P:glycogen metabolism (ISS)|alpha-1,4-glucan branching enzyme|6O" 17) "4540|UBC8|YEL012w,2E-35|C:cellular_component unknown (ISS)|F:ubiquitin conjugating enzyme (ISS)|P:monoubiquitination (ISS) | P:polyubiquitination (ISS)|E2 ubiquitin-conjugating enzyme|1S" 18) "1395|YER053c,2E-72|C:mitochondrion (ISS) | C:vacuole (sensu Fungi) (ISS)|F:inorganic phosphate transporter (ISS) | F:molecular_function unknown (ISS)|P:biological_process unknown (ISS)|mitochondrial phosphate carrier protein|2U" 19) "2659|YER067w,3E-20|conserved hypothetical protein|2" 20) 4216|HSP122|C:cellular_component unknown (ISS)|F:heat shock protein (ISS)|P:cell adhesion (ISS) | P:hyperosmotic response (ISS) | P:response to heat (ISS) | P:response to oxidative stress (ISS)|heat shock protein|5M 21) "1727|PMC1|YGL006w,0|C:vacuolar membrane (sensu Fungi) (ISS)|F:calcium- transporting ATPase (ISS) | F:calcium-transporting ATPase (ISS)|P:calcium ion homeostasis (ISS) | P:calcium ion transport (ISS) | P:calcium ion transport (ISS)|Ca2+-transporting P-type ATPase|3O" 22) "6684|PNC1|YGL037c,4E-19|C:cellular_component unknown (ND)|F:nicotinamidase (ISS)|P:chromatin silencing at ribosomal DNA (rDNA) (ISS) | P:chromatin silencing at telomere (ISS) | P:nicotinate nucleotide biosynthesis, salvage pathway (ISS)|pyrazinamidase/nicotinamidase|7" 23) "2768|AMS1|YGL156w,e-146|C:vacuolar membrane (ISS)|F:alpha-mannosidase (ISS)|P:carbohydrate metabolism (ISS)|vacuolar alpha mannosidase|4" 24) "1272|YGR111w,0.0000000000000001|conserved hypothetical protein|4H" 25) 988|conserved membrane protein|1E or 1L 26) "1788|XKS1|YGR194c,3E-88|F:xylulokinase (IEA)|P:xylulose catabolism (ISS)|xylulokinase|4F2" 27) "7131|YHL021c,3E-33|conserved hypothetical protein|7" 28) "1862|YHR087w,0.00000005|conserved hypothetical protein|2" 29) "4317|GRE3|YHR104w,5E-76|F:aldehyde reductase (ISS)|P:response to stress (ISS)|aldose reductase|5M" 30) "6167|AYR1|YIL124w,1E-56|C:cytoplasm (ISS) | C:endoplasmic reticulum (ISS) | C:lipid particle (ISS)|F:acylglycerone-phosphate reductase (ISS)|P:phosphatidic acid biosynthesis (ISS)|1-Acyl dihydroxyacetone phosphate reductase|RM \ S" 31) "86|GPX2|YIR037w,1E-47|C:cellular_component unknown (ND)|F:glutathione peroxidase (ISS) | F:glutathione peroxidase (ISS)|P:response to oxidative stress (ISS)|glutathione peroxidase|6O" 32) "6998|GST3|YIR038c,3E-24|C:endoplasmic reticulum (ISS)|F:glutathione transferase (ISS) | F:glutathione transferase (ISS)|P:glutathione metabolism (ISS)|glutathione S-transferase|3" 33) "2414|MPM1|YJL066c,0.00003|C:membrane fraction (ISS) | C:mitochondrion (ISS)|F:molecular_function unknown (ND)|P:biological_process unknown (ND)|mitochondrial membrane protein|R" 34) "6423|FBP26|YJL155c,7E-66|C:cytosol (ISS)|F:6-phosphofructo-2-kinase (ISS) | F:6-phosphofructo-2-kinase (ISS) | F:fructose-2,6- bisphosphate 2-phosphatase (ISS)|P:gluconeogenesis (ISS)|fructose-2,6-biphosphatase|RS or RU" 35) "6976|YJL163c,0.0000000003|multidrug efflux protein|3" 36) "7210|YJR008w,2E-43|conserved hypothetical protein|1S" 37) "6816|YJR096w,1E-61|C:cytoplasm (ISS)|F:molecular_function unknown (IEA)|P:biological_process unknown (IEA)|aldehyde reductase|3P" 38) "1738|UGP1|YKL035w,e-137|F:UTP-glucose-1-phosphate uridylyltransferase (IEA) | F:UTP-glucose-1-phosphate uridylyltransferase (ISS) | F:UTP-glucose-1-phosphate uridylyltransferase (ISS)|P:UDP-glucose metabolism (ISS) | P:protein amino acid glycosylation (ISS)|UTP-glucose-1-phosphate uridylyltransferase|R" 39) "4311|YNK1|YKL067w,3E-42|C:cellular_component unknown (ND)|F:nucleoside- diphosphate kinase (IEA) | F:nucleoside-diphosphate kinase (ISS)|P:biological_process unknown (ND)|nucleoside diphosphate kinase|5M" 40) "1628|LAP4|YKL103c,e-112|C:vacuole (sensu Fungi) (ISS)|F:vacuolar aminopeptidase I (IEA)|P:vacuolar protein catabolism (ISS) | P:vacuolar protein catabolism (ISS)|vacuolar aminopeptidase|3O" 41) "3844|MRP8|YKL142w,0.000000000000000004|C:mitochondrial ribosome (ISS) | C:mitochondrial ribosome (ISS)|F:structural constituent of ribosome (ISS) | F:structural constituent of ribosome (ISS)|P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS)|mitochondrial ribosomal protein|4F2" 42) "3507|MCR1|YKL150w,1E-62|C:mitochondrial intermembrane space (ISS) | C:mitochondrial outer membrane (ISS)|F:cytochrome b5 reductase (ISS)|P:electron transport (ISS) | P:ergosterol biosynthesis (ISS) | P:response to oxidative stress (ISS)|cytochrome b5 reductase|6O" 43) "3508|YKL151c,7E-37|hypothetical conserved protein|6O" 44) "820|SDS2|YKL193c,1E-54|C:cytoplasm (ISS) | C:nucleus (ISS)|F:enzyme regulator (ISS)|P:chromosome segregation (ISS) | P:protein targeting (ISS)|regulatory subunit for the mitotic function of type I protein phosphatase|2U" 45) "2613|ECM4|YKR076w,3E-73|C:cellular_component unknown (ND)|F:molecular_function unknown (ND)|P:cell wall organization and biogenesis (ISS)|involved in cell wall biogenesis and architecture|RMZ" 46) "6771|UBI4|UBI4|YLL039c,1E-77|C:cytoplasm (ISS)|F:protein degradation tagging (ISS) | F:protein tagging (ISS)|P:deubiquitination (ISS) | P:monoubiquitination (ISS) | P:polyubiquitination (ISS) | P:response to stress (ISS)|polyubiquitin involved in stress response system|3P" 47) "731|EMP46|YLR080w,0.0000000000001|C:Golgi membrane (ISS)|F:molecular_function unknown (IEA)|P:biological_process unknown (IEA)|involved in glycoprotein export from the endoplasmic reticulum|1" 48) "5125|YLR149c,5E-21|conserved hypothetical protein|7" 49) "1974|TFS1|YLR178c,1E-27|C:cellular_component unknown (ND)|F:lipid binding (ISS) | F:protease inhibitor (ISS)|P:biological_process unknown (ND)|carboxypeptidase Y inhibitor|5M" 50) "21|YLR251w,3E-32|MPV17 homolog|2" 51) "6901|DCS1|YOR173w,4E-57|similar to mRNA decapping enzyme|7" 52) 2107.1|STF2|ATP synthase regulatory factor|2U 53) "6058|GLO1|YML004c,1E-63|C:cellular_component unknown (ND)|F:lactoylglutathione lyase ((ISS))|P:glutathione metabolism ((ISS))|glyoxalase I|1S" 54) "7310|MSC1|YML128c,6E-40|C:cellular_component unknown (ND)|F:molecular_function unknown (ND)|P:meiotic recombination (ISS)|Meiotic Sister-Chromatid recombination|RS \ RB \ RB2 \ RD \ RU" 55) "7531|YMR090w,0.000000000000000002|conserved hypothetical protein|RM" 56) "2841|PGM2|YMR105c,e-146|C:cytosol (ISS)|F:phosphoglucomutase (ISS) | F:phosphoglucomutase (ISS) | F:phosphoglucomutase (ISS)|P:galactose metabolism (ISS) | P:glucose 1-phosphate utilization (ISS) | P:glucose 1-phosphate utilization (ISS) | P:glucose 6-phosphate utilization (ISS) | P:glucose 6-phosphate utilization (ISS) | P:glycogen metabolism (ISS) | P:trehalose biosynthesis (ISS)|phosphoglucomutase|R" 57) "6066|YMR110c,9E-73|conserved hypothetical protein|1S" 58) 1593|RIM11|GSK3|F:glycogen synthase kinase 3 ((ISS)) | F:glycogen synthase kinase 3 (ISS) | F:protein kinase (IEA)|P:meiosis (IEA) | P:protein amino acid phosphorylation ((ISS)) | P:protein amino acid phosphorylation (ISS) | P:proteolysis and peptidolysis ((ISS))|ser/thr protein kinase | glycogen synthase kinase 3|2 59) "338|YMR196w,0|conserved hypothetical protein|3O" 60) "337|VTI1|YMR197c,4E-20|C:Golgi membrane, integral protein (ISS)|F:v-SNARE (ISS)|P:Golgi to vacuole transport (ISS) | P:endosome to lysosome transport (ISS) | P:intra-Golgi transport (ISS) | P:non-selective vesicle fusion (ISS)|v-SNARE involved in several protein transport steps|3O" 61) "1153|GAD1|YMR250w,1E-89|C:cytoplasm (ISS)|F:glutamate decarboxylase (IEA)|P:amino acid metabolism (ISS)|glutamate decarboxylase|1X" 62) "1339|CPY1|CPY1|YMR297w,e-134|C:cytoplasm (ISS) | C:endoplasmic reticulum (ISS)|F:carboxypeptidase C (ISS)|P:vacuolar protein catabolism (ISS)|serine carboxypeptidase Y precursor|7" 63) 5525|conserved hypothetical protein|6O 64) 1183|conserved hypothetical protein|6O 65) "3679|YNL200c,2E-25|conserved hypothetical protein|1SZ" 66) "2989|YNL274c,6E-63|P:biological_process unknown (IEA)|glycerate/formate- dehydrogenase|1SZ" 67) "916|YNL305c,0.0000000000005|conserved hypothetical membrane protein|" 68) "4393|CIT1|YNR001c,e-135|C:mitochondrial matrix (ISS) | C:mitochondrion (ISS)|F:citrate (SI)-synthase (ISS)|P:citrate metabolism (ISS) | P:glutamate biosynthesis (ISS) | P:tricarboxylic acid cycle (ISS)|nuclear citrate synthase|R" 69) "6405|YAL018c,0.00000001|conserved hypothetical membrane protein|RS or RU" 70) "4727|EMI5|YOL071w,1E-24|Early Meiotic Induction|1J \ 1S" 71) 5813|conserved hypothetical protein|2U 72) "6757|GCY1|YOR120w,3E-57|C:cellular_component unknown (ND)|F:aldo-keto reductase (ISS)|P:salinity response (IEP)|similar to mammalian aldo/keto reductases|3P" 73) "6554|YOR220w,0.0006|conserved hypothetical protein|7F" 74) "2047|YOR289w,0.00000000000000004|conserved hypothetical protein|2U" 75) "3104|YDC1|YPL087w,3E-54|P:sphingolipid metabolism (IEA)|alkaline dihydroceramidase|4H" 76) "3926|RNY1|YPL123c,4E-44|P:biological_process unknown (IEA)|ribonuclease from the T2 family|5I" 77) "1891|36616|36616|YPL154c,e-105|C:vacuole (sensu Fungi) (ISS)|F:endopeptidase (ISS) | F:saccharopepsin (ISS)|P:response to starvation (ISS) | P:vacuolar protein catabolism (ISS) | P:vacuolar protein catabolism (ISS)|vacuolar aspartic proteinase precursor|2" 78) "3665|SET6|YPL165c,4E-40|putative HLH transcription factor|1SZ" 79) 243|OXR1|C:cellular_component unknown (ND)|F:molecular_function unknown (ND)|P:response to oxidative stress (ISS)|resistance to oxidation|3O 80) "2277|TPK2|TPK2|YPL203w,e-121|C:cAMP-dependent protein kinase complex (ISS) | C:cytoplasm (ISS)|F:cAMP-dependent protein kinase (ISS) | F:protein serine/threonine kinase (ISS)|P:RAS protein signal transduction (ISS) | P:protein amino acid phosphorylation (ISS) | P:pseudohyphal growth (ISS)|cAMP-dependent protein kinase catalytic subunit|2U" 81) "723|USV1|YPL230w,0.000000000000005|conserved hypothetical protein|1" 82) "7021|GPH1|YPR160w,0|F:glycogen phosphorylase (ISS)|P:glycogen catabolism (ISS)|glycogen phosphorylase|7C \ 7A" 83) "744|GDB1|YPR184w,0|C:cellular_component unknown (ND)|F:4-alpha- glucanotransferase (ISS) | F:4-alpha-glucanotransferase (ISS) | F:4-alpha-glucanotransferase (ISS) | F:amylo-1,6- glucosidase (ISS) | F:amylo-1,6-glucosidase (ISS) | F:amylo-1,6-glucosidase (ISS)|P:glycogen catabolism (ISS)|glycogen debranching enzyme|4" ----------------------------------------------- -----------------------------------------------